喬傑(中國工程院院士、生殖醫學專家)

喬傑(中國工程院院士、生殖醫學專家)

 喬傑，1964年01月02日出生，黑龍江省哈爾濱市人，生殖醫學專家，北京大學第三醫院院長，中國工程院院士，醫學博士，教授，博士生導師，主任醫師。

1987年畢業於北京醫科大學，1996年獲得博士學位。曾在香港大學做訪問學者、美國史丹福大學做博士後研究，現任北京大學第三醫院院長、婦產科主任、生殖醫學中心主任。是國家傑出青年科學基金獲得者，中華醫學會生殖醫學分會第三屆委員會主任委員、中國醫師協會生殖醫學專業委員會第一屆主任委員，《中華生殖與避孕雜誌》總編。

喬傑多年來一直從事婦產及生殖健康相關臨床與基礎研究工作。

基本介紹

  • 中文名：喬傑
  • 國籍：中國
  • 出生地：黑龍江省哈爾濱市
  • 出生日期：1964年01月02日
  • 職業：教育科研工作者
  • 畢業院校：北京醫科大學
  • 主要成就：2017年當選為中國工程院院士
人物經歷,社會任職,主要成就,科研成就,榮譽表彰,學術成就,科研項目,

人物經歷

1981年9月－1987年7月，北京醫科大學醫學系，獲學士學位。
1987年9月－1990年7月，北醫大第三醫院婦產科，獲醫學碩士學位。
1993年9月－1996年8月，北醫大第三醫院婦產科，獲博士學位。
2002年9月－2003年8月，Stanford University Medical Center,USA. 博士後研究。
1990.08－1992.11 ，北京醫科大學第三醫院婦產科住院醫師。
1992.12－1997.09 ，北京醫科大學第三醫院婦產科主治醫師。
1996.09－1997.03 及1997.10－1997.11，香港大學瑪麗醫院（Queen Mary Hospital）婦產科訪問學者並獲香港臨時註冊醫師資格。
1997.10－2001.05，北京醫科大學第三醫院婦產科副主任醫師、副教授。
2001.06－至今，北京大學第三醫院婦產科主任醫師，教授。
2000.10－2018.07，北京大學第三醫院婦產科主任。
2003.03－2018.07，北京大學第三醫院生殖醫學中心主任。
2003.3－2012.5，北京大學第三醫院黨委副書記。
2012.05－至今，北京大學第三醫院院長。

社會任職

  • 國際
2016-至今，主席, 國際生育學會聯合會科學委員會（IFFS）董事會成員兼地方理事會主席。
2012-2013 主席，全球華人生殖醫學聯合會。
2011-2013 ，主席，美國生殖醫學會GCARM & ChSIG （GCARM &ChSIG of ASRM）。
  • 國內
2019-至今，國家衛生健康標準委員會專業委員會委員。
2019-至今，國家生命科學和醫學研究倫理委員會委員。
2018-至今，副主任委員，中華醫學會婦產科學分會副主任委員。
2018-至今，副理事長，中國遺傳學會。
2018-至今，會長，中國女醫師協會。
2018-至今，主任，國家衛生和計畫生育委員會生殖健康重點實驗室學術委員會。
2018-至今，常務理事, 中國醫師協會第四屆理事會。
2016-至今，委員，教育部科學技術委員會生物與醫學學部。
2016-至今，委員，中科院動物所幹細胞與生殖生物學國家重點實驗室第六屆學術委員會。
2016-至今，國際生育學會聯合會科學委員會（IFFS）董事會成員兼地方理事會主席。
2015-至今，主任，中國醫師協會生殖醫學專業委員會。
2015-至今，所長, 生殖健康和中西醫研究所。
2015-至今，主任，國家婦產科疾病臨床研究中心。
2012-2015，主任委員，中華醫學會生殖醫學分會第三屆委員會。
2012-至今 ，主任委員，北京醫學會生殖醫學分會。
2012-至今，委員，世界高雄激素與多囊卵巢綜合徵學會(AE-PCOS)。
2011-至今 ，主任，教育部輔助生殖重點實驗室主任。
2011-至今，主任，北京生殖內分泌和輔助生殖重點實驗室主任。
2008 -至今，主任，衛生部輔助生殖技術培訓基地。
  • 學術雜誌審稿人
Lancet
Human Reproduction
EJOG
BJOG
Fertility and sterility
RBM online
  • 學術著作編委
2018-至今，顧問， 《NEJM醫學前沿顧問》。
2018-至今，主編， Human Reproduction Update (中文版)。
2015-至今，主編， 《中國微創外科雜誌》。
2012-至今，主編， 《生殖與避孕雜誌》。
2011-至今，編委， Journal of Reproductive Biology and Endocrinology。
2010-至今，編委， Journal of Seminars in Reproductive Medicine。
2010-至今，編委， 《亞洲男科雜誌》。

主要成就

科研成就

  • 科研綜述
作為科技部“生殖與發育重大專項”首席科學家、教育部長江學者特聘教授、國家自然科學基金創新研究群體“生殖細胞發育”首席專家，喬傑一直從事婦產科及生殖健康相關的臨床與基礎研究工作，從遺傳學、表觀遺傳學角度對人類早期胚胎髮育機制進行了深入的研究，將基礎研究成果成功套用於臨床上胚胎植入前遺傳學診斷；揭示疑難不孕症發病機制，最佳化輔助生殖技術方法，提高疑難不孕患者治療成功率。
  • 科研成果
研究成果連續入選2014、2015年度中國科學十大進展。
2018年，第十一屆談家楨生命科學獎。
2017年，國家科技進步二等獎（第一完成人）。
2016華，夏醫學科技獎一等獎（第一完成人）。
2011年，何梁何利基金科技與技術進步獎。
2011年，國家科技進步二等獎（第一完成人）。
2011年，北京市科技進步二等獎（第一完成人）。
2009年，國家科技進步獎二等獎（第二完成人）。

榮譽表彰

1998年，北京市北京高校第二屆青年教師教學基本功大賽三等獎。
2000年，北京市北京高校第三屆青年教師教學基本功大賽二等獎。
2002年，教育部第四屆“高校青年教師獎”。
2008年，教育部高校科學進步獎一等獎（第一完成人）。
2008年，國家傑出青年科學基金。
2009年，中國女醫師協會五洲女子科技獎“臨床醫學科研創新獎”。
2010年，教育部創新團隊獎。
2010年，“長江學者特聘教授”。
2010年，入選2009年“新世紀百千萬人才工程”國家級人選名單。
2010年，北京大學醫學部“優秀黨員”。
2011年，北京大學醫學部教學管理優秀獎。
2011年，CMB傑出教授獎。
2012年，年度“科技北京”百名領軍人才培養工程。
2013年，華夏醫學科技獎二等獎（第一完成人）。
2013年，第十四屆吳階平-保羅.楊森醫學藥學獎（吳楊獎）。
2013年，年度北京市“優秀教師”。
2014年，中國僑界貢獻獎--創新團隊。
2014年藥明康德生命化學研究獎”--成就獎。
2014年，科技盛典--中央電視台科技創新人物。
2015年，國家衛生計生突出貢獻中青年專家。
2015年，第八屆中華人口獎科學技術獎。
2016年，全國傑出科技人才。
2016年，中國醫院協會優秀醫院院長。
2016年，全國優秀科技工作者。
2016年，中國醫學科學家獎。
2017年，當選為中國工程院院士。
2017年，中國醫療保健國際交流促進會優秀學科帶頭人。
2017年，中源協和生命醫學成就獎。
2017年，北京市高等教育教學成果獎二等獎。
2018年，中華醫學科技獎一等獎。

學術成就

以生殖調控相關的基礎研究和不孕症相關疾病發病機制及診療新技術的研發為核心，在揭示人類配子/胚胎/原始生殖細胞發育過程的遺傳和表觀遺傳調控規律、創建新型卵母細胞體外成熟體系和提高疑難不孕患者治療成功率等方面做出突出貢獻：
1.建立人類精卵遺傳圖譜及早期胚胎、原始生殖細胞的基因表達譜和甲基化圖譜，明確調節胚胎髮育關鍵基因；
2.發現炎症因子影響卵母細胞質量導致不孕新機制，創立子宮內膜容受性評估和治療新方法，改進卵母細胞及胚胎凍存技術，顯著提高妊娠成功率；
3.發現多囊卵巢綜合徵(PCOS)發病炎性機制，建立其代謝異常預測模型，提供預防其長期合併症的新策略，制定適用於中國PCOS的診斷標準。
  • 學術論著
第一或通訊作者SCI文章目錄
    1. Qiao J, Yeung WSB, Yao YQ, Ho PC. The effects of follicular fluid from patients with different indications for IVF treatment on the binding of human spermatozoa to the zona pellucida. Hum Reprod (1998), 13(1)128-131.
    2. Zhen XM, Qiao J*, Li R, Wang LN, Liu P. The clinical analysis of poor ovarian response in in-vitro-fertilization embryo-transfer among Chinese couples. J Assist Reprod Genet (2008), 25:17-22.
    3. Wang L, Qiao J*, Liu P, Lian Y. Effect of luteinized unruptured follicle cycles on clinical outcomes of frozen thawed embryo transfer in Chinese women. J Assist Reprod Genet (2008), 25:229-233.
    4. Qiao J*, Wang L, Li R, Zhang X. Microarray evaluation of endometrial receptivity in Chinese women with polycystic ovary syndrome. Reprod Biomed Online (2008), 17: 425-435.
    5. Ma C, Qiao J*, Liu P, Chen G. Ovarian suppression treatment prior to in-vitro fertilization and embryo transfer in Chinese women with stage III or IV endometriosis. Int J Gynaecol Obstet (2008), 100:167-70.
    6. Li R, Qiao J*, Wang L, Zhen X, Lu Y. Serum progesterone concentration on day of HCG administration and IVF outcome. Reprod Biomed Online (2008), 16:627-631.
    7. Li HZ. Chen XN, Qiao J*. Letrozole as primary therapy for endometrial hyperplasia in young women. Int J Gynaecol Obstet (2008), 100:10-12.
    8. Yan LY, Qiao J*, Chen Y, Huang J, Liu P, Sun QY. Application of three-dimensional fluorescence in situ hybridization to human preimplantation genetic diagnosis. Fertil Steril (2009), 92: 1492-1495.
    9. Chen Y, Zhao S, Qiao J*, Liu P, Lian Y, Zheng X. Expression of bone morphogenetic protein-15 in human oocyte and cumulus granulosa cells primed with recombinant follicle-stimulating hormone followed by human chorionic gonadotropin. Fertil Steril (2009), 92:2045-2046.
    10. Chen Y, Qiao J*, Yan LY, Huang S, Zhao PL, Yan J. Selective impairment in glycogen synthase kinase-3 and mitogen-activated protein kinase phosphorylation: comparisons with the hyperandrogenic and the hyperinsulinemic rats. Fertil Steril (2009), 92:1447-1455.
    11. Han C, Zhang Q, Ma R, Xie L, Qiu T, Wang L, Mitchelson K, Wang J, Huang G*, Qiao J*, Cheng J. Integration of single oocyte trapping, in vitro fertilization and embryo culture in a microwell-structured microfluidic device. Lab Chip (2010), 10, 2848-54.
    12. Huang S, Qiao J*, Li R, Wang L, Li M. Can serum apolipoprotein C-I demonstrate metabolic abnormality early in women with polycystic ovary syndrome? Fertil Steril (2010), 94(1):205-210.
    13. Qiao J*, Chen Y, Yan LY, Yan J, Liu P, Sun QY. Changes in histone methylation during human oocyte maturation and IVF- or ICSI-derived embryo development. Fertil Steril (2010), 93: 1628-36.
    14. Zhao SY, Qiao J*, Chen YJ, Liu P, Li J, Yan J. Expression of growth differentiation factor-9 and bone morphogenetic protein-15 in oocytes and cumulus granulosa cells of patients with polycystic ovary syndrome. Fertil Steril (2010), 94:261-267.
    15. Yang Y, Qiao J*, Tang RX, Li MZ. Genotype and haplotype determination of interleukin (IL) 1 beta (g. -511C>T and g. +3954C>T) and IL-1RN in polycystic ovary syndrome. Fertil Steril (2010), 94:384-386
    16. Ma CH, Yan LY, Qiao J*, Sha W, Li L, Chen Y, Sun QY. Effects of tumor necrosis factor-alpha on porcine oocyte meiosis progression, spindle organization, and chromosome alignment. Fertil Steril (2010), 93:920-926.
    17. Lin SL, Yan LY, Zhang XT, Yuan J, Li M, Qiao J*, Wang ZY, Sun QY. ER-alpha36, a variant of ER-alpha, promotes tamoxifen agonist action in endometrial cancer cells via the MAPK/ERK and PI3K/Akt pathways. Plos One (2010), 5:e9013.
    18. Chi H, Qiao J*, Li H, Liu P, Ma C. Double measurements of serum HCG concentration and its ratio may predict IVF outcome. Reprod Biomed Online (2010), 20:504-509.
    19. Yan LY, Yan J, Qiao J*, Zhao PL, Liu P. Effects of oocyte vitrification on histone modifications. Reprod Fertile Dev (2010), 22:920-925.
    20. Zhang Q, Bai Q, Yuan Y, Liu P, Qiao J*. Assessment of seminal estradiol and testosterone levels as predictors of human spermatogenesis. J Androl (2010), 31:215-220.
    21. Zhao W, Qiao J*, Zhang Q, Zhao Y, Chen Q. Levels of antiangiogenic factors in preeclamptic pregnancies. Growth Factors (2010), 28:293-298.
    22. Yang Y, Qiao J*, Li MZ. Association of polymorphisms of interleukin-18 gene promoter region with polycystic ovary syndrome in Chinese population. Reprod Biol Endocrinol (2010), 8:125.
    23. Wang L, Qiao J*, Li R, Zhen X, Liu Z. Role of endometrial blood flow assessment with color Doppler energy in predicting pregnancy outcome of IVF-ET cycles. Reprod Biol Endocrinol (2010), 8:122.
    24. Zhen X, Qiao J*, Ma C, Fan Y, Liu, P. Intraperitoneal bleeding following transvaginal oocyte retrieval. Int J Gynaecol Obstet (2010), 108:31-34.
    25. Zhao YY, Xiong GW, Ma CH, Wei Y, Wang LN, Qiao J*. Application of fetoscopy in the management of monochorionic multiple pregnancies. Chin Med J (Engl) (2010), 123:105-107.
    26. Ma CH, Yang S, Qiao J*, Yang Y, Liu P. Evaluation of the tissue damage of porcine ovaries after bipolar drilling under transvaginal hydrolaparoscopy--an in vitro experiment. Gynecol Endocrinol (2010), 26(7):549-553.
    27. Yan J, Suzuki J, Yu X, Kan FW, Qiao J*, Chian RC. Cryo-survival, fertilization and early embryonic development of vitrified oocytes derived from mice of different reproductive age. J Assist Reprod Genet (2010), 27:605-611.
    28. Ma YM, Li R, Qiao J*, Zhang XW, Wang SY, Zhang QF, Li L, Tu BB, Zhang X. Characteristics of abnormal menstrual cycle and polycystic ovary syndrome in community and hospital populations. Chin Med J (Engl) (2010), 123:2185-2189.
    29. Li HZ, Qiao J*, Chi HB, Chen XN, Liu P, Ma CH. Comparison of the major malformation rate of children conceived from cryopreserved embryos and fresh embryos. Chin Med J (Engl) (2010), 123:1893-1897.
    30. Li H, Qiao J*, Guo H. 17-alpha-hydroxylase deficiency: a case report with clinical and molecular analysis. Gynecol Endocrinol (2010), 26(7):521-523.
    31. Huang XW, Qiao J*, Xia EL, Ma YM, Wang Y. Effect of interval after surgery on in vitro fertilization/ intracytoplasmic sperm injection outcomes in patients with stage III/IV endometriosis. Chin Med J (Engl) (2010) 123(16):2176-2180.
    32. Yu Y, Yan J, Liu ZC, Yan LY, Li M, Zhou Q, Qiao J*. Optimal timing of oocyte maturation and its relationship with the spindle assembly and developmental competence of in vitro matured human oocytes. Fertil Steril (2011), 96:73-78.
    33. Yan J, Yang Y, Yan LY, Liu ZC , Liu P, Feng HL, Zhou Q, Qiao J*. In vitro maturation of cumulus-partially enclosed immature human oocytes by priming with gonadotropin. Fertil Steril (2011), 96:629-634.
    34. Tu BB, Lin SL, Yan LY, Wang ZY, Sun QY*, Qiao J*. ER-α36, a novel variant of estrogen receptor α, is involved in EGFR-related carcinogenesis in endometrial cancer. Am J Obstet Gynecol (2011), 205(3):227.
    35. Li L, Shi J, Zhang QF, Yan J, Yan LY, Shen F, Qiao J*, Feng HL. Effect of curettage and copper wire on rabbit endometrium: a novel rabbit model of endometrial mechanical injury. Chin Med J (Engl) (2011), 124(11):1708-1713.
    36. Yan J, Suzuki J, Yu XM, Qiao J*, Kan FW, Chian RC. Effects of duration of cryo-storage of mouse oocytes on cryo-survival, fertilization and embryonic development following vitrification. J Assist Reprod Genet (2011), 28:643-649.
    37. Yang R, Ma C*, Qiao J*, Li TC, Yang Y, Chen X, Yang S, Liu P. The usefulness of transvaginal hydrolaparoscopy in infertile women with abnormal hysterosalpingogram results but with no obvious pelvic pathology. Eur J Obstet Gynecol Reprod Biol (2011), 155(1):41-43.
    38. Zhang X, Fu L, Zhang Q, Yan L, Ma Y, Tu B, Liu N, Qiao J*. Association of TRB3 Q84R polymorphism with polycystic ovary syndrome in Chinese women. Reprod Biol Endocrinol (2011), 9:46.
    39. Hu W, Qiao J*, Yang Y, Wang L, Li R. Elevated C-reactive protein and monocyte chemoattractant protein-1 in patients with polycystic ovary syndrome. Eur J Obstet Gynecol Reprod Biol (2011), 157:53-56.
    40. Huang S, Zhao P, Yang L, Chen Y, Yan J, Duan E, Qiao J*. Fractalkine is expressed in the human ovary and increases progesterone biosynthesis in human luteinized granulosa cells. Reprod Boil Endocrinol (2011), 9:95.
    41. Zhang QF, Feng HL, Zhao L, Liu P, Li L, Yan J, Qiao J*. Alteration of erbeta gene rsai polymorphism may contribute to reduced fertilization rate and embryonic developmental competence. Asian J Androl (2011), 13:317-321.
    42. Li R, Qiao J*, Wang L, Li L, Zhen X, Liu P, Zheng X. Microrna array and microarray evaluation of endometrial receptivity in patients with high serum progesterone levels on the day of hCG administration. Reprod Biol Endocrinol (2011), 9:29.
    43. Yang Y, Qiao J*, Li R, Li MZ. Is interleukin-18 associated with polycystic ovary syndrome? Reprod Biol Endocrinol (2011), 9:7.
    44. Hu W, Qiao J*. Expression and regulation of adipocyte fatty acid binding protein in granulosa cells and its relation with clinical characteristics of polycystic ovary syndrome. Endocrine (2011), 40:196-202.
    45. Zhao P, Qiao J*, Huang S, Zhang Y, Liu S, Yan LY, Hsueh AJ, Duan EK. Gonadotrophin-induced paracrine regulation of human oocyte maturation by BDNF and GDNF secreted by granulosa cells. Hum Reprod (2011), 26:695-702.
    46. Zhao Y, Fu L, Li R, Wang LN, Yang Y, Liu NN, Zhang CM, Wang Y, Liu P, Tu BB, Zhang X, Qiao J*. Metabolic profiles characterizing different phenotypes of polycystic ovary syndrome: plasma metabolomics analysis. BMC Med (2012), 10:153.
    47. Sun L, Hu W, Liu Q, Hao Q, Sun B, Zhang Q, Mao S, Qiao J*, Yan X*. Metabonomics reveals plasma metabolic changes and inflammatory marker in polycystic ovary syndrome patients. J Proteome Res (2012), 11:2937-2946.
    48. Hu W, Marchesi D, Qiao J*, Feng HL. Effect of slow freeze versus vitrification on the oocyte: an animal model. Fertil steril (2012), 98:752-760.
    49. Yu Y, Yan J, Li M, Yan L, Zhao Y, Lian Y, Li R, Liu P, Qiao J*. Effects of combined epidermal growth factor, brain-derived neurotrophic factor and insulin-like growth factor-1 on human oocyte maturation and early fertilized and cloned embryo development. Hum Reprod (2012), 27, 2146-59.
    50. Li M, Yu Y, Yan J, Yan LY, Zhao Y, Li R, Liu P, Hsueh AJ, Qiao J*. The role of cilostazol, a phosphodiesterase 3 inhibitor, on oocyte maturation and subsequent pregnancy in mice. Plos One (2012), 7:e30649.
    51. Wu Z, Li R, Ma Y, Deng B, Zhang X, Meng Y, Chen X, Liu P, Qiao J*. Effect of HCG-day serum progesterone and oestradiol concentrations on pregnancy outcomes in GnRH agonist cycles. Reprod Biomed Online (2012), 24:511-520.
    52. Liu N, Ma Y, Li R, Jin H, Li M, Huang X, Feng HL, Qiao J*. Comparison of follicular fluid amphiregulin and EGF concentrations in patients undergoing IVF with different stimulation protocols. Endocrine (2012), 42:708-716.
    53. Zheng X, Wang L, Zhen X, Lian Y, Liu P, Qiao J*. Effect of hcg priming on embryonic development of immature oocytes collected from unstimulated women with polycystic ovarian syndrome. Reprod Biol Endocrinol (2012), 10:40.
    54. Liu N, Ma Y, Wang S, Zhang X, Zhang Q, Fu L, Qiao J*. Association of the genetic variants of luteinizing hormone, luteinizing hormone receptor and polycystic ovary syndrome. Reprod Biol Endocrinol (2012), 10:36.
    55. Zhang K, Han J, Yao Y, Yang J, Qiao J*.Local reaction to the different meshes at the vesicovaginal space in rabbit model. Int Urogynecol J (2012), 23(5):605-611.
    56. Ma C, Wang Y, Li TC, Qiao J*, Yang Y, Song X, Yang S. Trans-abdominal ultrasound guided transvaginal hydrolaparoscopy is associated with reduced complication rate. Eur J Obstet Gynecol Reprod Biol (2012), 160:166-169.
    57. Qiao J, Lu G, Zhang HW, Chen H, Ma C, Olofsson JI, Witjes H, Heijnen E , Mannaerts B. A randomized controlled trial of the GnRH antagonist Ganirelix in Chinese normal responders: high efficacy and pregnancy rates. Gynecol Endocrinol (2012), 28:800-804.
    58. Huang X, Bai Q, Yan LY, Zhang QF, Geng L, Qiao J*. Combination of serum inhibin B and follicle-stimulating hormone levels can not improve the diagnostic accuracy on testicular sperm extraction outcomes in Chinese non-obstructive azoospermic men. Chin Med J (Engl) (2012), 125(16):2885-2889.
    59. Li R, Qiao J*, Yang D, Li S, Lu S, Wu X, Wei Z. Epidemiology of hirsutism among women of reproductive age in the community: a simplified scoring system. Eur J Obstet Gynecol Reprod Biol (2012), 163:165-169.
    60. Hou Y, Fan W, Yan L, Li R, Lian Y, Huang J, Li J, Xu L, Tang F*, Xie XS*, Qiao J*. Genome analyses of single human oocytes. Cell (2013), 155:1492-1506. Highlighted by Erika Check Hayden, Nature (2013).
    61. Yan L, Yang M, Guo H, Yang L, Wu J, Li R, Li P, Lian Y, Zheng X, Yan J, Huang J, Li M, Wu X, Wen L, Lao K, Li RQ *, Qiao J*, Tang F*. Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells. Nat Struct Molbiol (2013), 20:1131-1139. Highlighted by Charlotte Schubert, Biology of Reproduction (2013).
    62. Qiao J, Wang ZB, Feng HL, Miao YL, Wang Q, Yu Y, Wei YC, Yan J, Wang WH, Shen W, Sun SC, Schatten H, Sun QY*. The root of reduced fertility in aged women and possible therapeutic options: Current status and future prospects. Mol Aspects Med (2013), 38:54–85.
    63. Fan Y, Li R, Huang J, Yu Y*, Qiao J*. Diploid, but not haploid, human embryonic stem cells can be derived from microsurgically repaired tripronuclear human zygotes. Cell Cycle (2013), 12:302-311.
    64. Yu Y, Zhao Y, Li R, Li L, Zhao H, Li M, Sha J, Zhou Q, Qiao J*. Assessment of the risk of blastomere biopsy during preimplantation genetic diagnosis in a mouse model: reducing female ovary function with an increase in age by proteomics method. J Proteome Res (2013), 12:5475-5486.
    65. Zhao, HC, Zhao Y, Li M, Yan J, Li L, Li R, Liu P, Yu Y, Qiao J*. Aberrant epigenetic modification in murine brain tissues of offspring from preimplantation genetic diagnosis blastomere biopsies. Biol Reprod (2013), 89: 117.
    66. Yu Y, Yan J, Zhang Q, Yan L, Li M, Zhou Q, Qiao J*. Successful reprogramming of differentiated cells by somatic cell nuclear transfer, using in vitro-matured oocytes with a modified activation method. J Tissue Engregen Med (2013), 7(11):855-863.
    67. Li H, Chen Y, Yan LY, Qiao J*. Increased expression of p450scc and CYP17 in development of endogenous hyperandrogenism in a rat model of PCOS. Endocrine (2013), 43(1):184-190.
    68. Liu XH, Qiao J*, Li R, Yan LY, Chen LX. Y chromosome azfcmicrodeletion may not affect the outcomes of ICSI for infertile males with fresh ejaculated sperm. J Assist Reprod Genet (2013), 30:813-819.
    69. Li R, Zhang Q, Yang D, Li S, Lu S, Wu X, Wei Z, Song X, Wang X, Fu S, Lin J, Zhu Y, Jiang Y, Feng HL, Qiao J*. Prevalence of polycystic ovary syndrome in women in China: a large community-based study. Hum Reprod (2013), 28:2562-2569.
    70. Li M, Zhao Y, Zhao CH, Yan J, Yan YL, Rong L, Liu P, Feng HL, Yu Y, Qiao J*. High FSH decreases the developmental potential of mouse oocytes and resulting fertilized embryos, but does not influence offspring physiology and behavior in vitro or in vivo. Hum Reprod (2013), 28:1309-1323.
    71. Gao, JM, Yan J, Li R, Li M, Yan LY, Wang TR, Zhao HC, Zhao Y, Yu Y, Qiao J*. Improvement in the quality of heterotopic allotransplanted mouse ovarian tissues with basic fibroblast growth factor and fibrin hydrogel. Hum Reprod (2013), 28:2784-2793.
    72. Wang X, Tsai T, Qiao J*, Zhang Z, Feng HL*. Impact of gonadotropins on oocyte maturation, fertilisation and developmental competence in vitro. Reprod Fertil Dev (2013), 26(5):752-757.
    73. Lin SL, Tu BB, Du XG, Yan LY, Qiao J*. Lower expression of ER-α36 is associated with the development of endometrial hyperplasia in PCOS patients. Histol Histopathol (2013), 28(11):1491-1498.
    74. Guo HS, Zhu P, Yan LY, Li R, Hu BQ, Lian Y, Yan J, Ren XL, Lin SL, Li JS, Jin XH, Shi XD, Liu P, Wang XY, Wang W, Wei Y , Li XL, Guo F, Wu XL, Fan XY, Yong J, Wen L, Xie S X, Tang FC *, Qiao J*. The DNA methylation landscape of human early embryos. Nature (2014), 511:606–610.
    75. Wen L, Li X, Yan L, Tan Y, Li R, Zhao Y, Wang Y, Xie J, Zhang Y, Song C, Yu M, Liu X, Zhu P, Li X, Hou Y, Guo H, Wu X, He C*, Li R*, Tang F*, Qiao J*. Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain. Genome Biology (2014), 15(3): R49.
    76. Zhuang XJ, Shi YQ, Xu B, Chen L, Tang WH, Huang J, Lian Y, Liu P*, Qiao J*. SLX2 interacting with BLOS2 is differentially expressed during mouse oocyte meiotic maturation. Cell Cycle (2014), 13(14):2230-2236.
    77. Huang J, Yan L, Fan W, Zhao N, Zhang Y, Tang F, Xie XS, Qiao J*. Validation of multiple annealing and looping-based amplification cycle sequencing for 24-chromosome aneuploidy screening of cleavage-stage embryos. Fertil Steril (2014), 102(6):1685-1691.
    78. Li R, Yu G, Yang D, Li S, Lu S, Wu X, Wei Z, Song X, Wang X, Fu S, Qiao J*. Prevalence and predictors of metabolic abnormalities in Chinese women with PCOS: a cross- sectional study. BMC Endocr Disord (2014), 14:76.
    79. Lin S, Li R, Chi H, Huang S, Zhang H, Zheng X, Liu P, Qiao J*. Effect of ABO blood type on ovarian reserve in Chinese women. Fertil Steril (2014), 102(6):1729-1732 e1722.
    80. Tang W, Yan J, Wang T, Xia X, Zhuang X, Hong K, Li R, Liu P, Jiang H, Qiao J*. Up-regulation of heme oxygenase-1 expression modulates reactive oxygen species level during the cryopreservation of human seminiferous tubules. Fertil Steril (2014), 102(4):974-980.
    81. Zhao PL, Zhang QF, Yan LY, Huang S, Chen Y, Qiao J*. Functional investigation on aromatase in endometrial hyperplasia in polycystic ovary syndrome cases. Asian Pac J Cancer Prev (2014), 15(20):8975-8979.
    82. Zhu J, Li M, Chen L, Liu P, Qiao J*. The protein source in embryo culture media influences birthweight: a comparative study between G1 v5 and G1-PLUS v5. Hum Reprod (2014), 29(7):1387-1392.
    83. Wang TR, Yan LY, Yan J, Lu CL, Xia X, Yin TL, Zhu XH, Gao JM, Ding T, Hu WH, Guo HY, Li R, Qiao J*. Basic fibroblast growth factor promotes the development of human ovarian early follicles during growth in vitro. Hum Reprod (2014), 29(3):568-76.
    84. Fan Y, Li R, Huang J, Zhao HC, Ding T, Sun X, Yu Y*, Qiao J*. Improved efficiency of microsurgical enucleated tripronuclear zygotes development and embryonic stem cell derivation by supplementing epidermal growth factor, brain-derived neurotrophic factor, and insulin-like growth factor-1. Stem Cells Dev (2014), 23(6):563-575.
    85. Li Z, Liu W, Qiu T, Xie L, Chen W, Liu R, Lu Y, Mitchelson K, Wang J, Qiao J*, Cheng J*. The construction of an interfacial valve-based microfluidic chip for thermotaxis evaluation of human sperm. Biomicro fluidics (2014), 8(2):024102.
    86. Lu CL, Wang TR, Yan LY, Xia X, Zhu XH, Li R, Zhao HC, Yan J, Yin TL, Jin HY, Zhang Y, Zhang WX, Feng HL*, Qiao J*. Gonadotropin-mediated dynamic alterations during bovine oocyte maturation in vitro. Biol Reprod (2014), 91(2):44.
    87. Zhen X, Qiao J*, Li R, Wang L, Liu P. Serologic autoimmunologic parameters in women with primary ovarian insufficiency. BMC Immunol (2014), 15:11.
    88. Zhang CM, Zhao Y, Li R, Yu Y, Yan LY, Li L, Liu NN, Liu P, Qiao J*. Metabolic heterogeneity of follicular amino acids in polycystic ovary syndrome is affected by obesity and related to pregnancy outcome. BMC Pregnancy Childbirth (2014), 14:11.
    89. Yang R, Du X, Wang Y, Song X, Yang Y, Qiao J*. The hysteroscopy and histological diagnosis and treatment value of chronic endometritis in recurrent implantation failure patients. Arch Gynecol Obstet (2014), 289(6):1363-1369.
    90. Liu XH, Yan LY, Lu CL, Li R, Zhu XH, Jin HY, Zhang Y, Zhang WX, Gao SH and Qiao J*. ART does not increase the risk of Y-chromosome microdeletion in 19 candidate genes at AZF regions. Reprod Fertil Dev (2014), 26(6):778-786.
    91. Wu D, Chi H, Shao M, Wu Y, Jin H, Wu B, Qiao J*. Prenatal diagnosis of Down syndrome using cell-free fetal DNA in amniotic fluid by quantitative fluorescent polymerase chain reaction. Chin Med J (Engl) (2014), 127(10):1897-1901.
    92. Yan L, Huang L, Xu L, Huang J, Ma F, Zhu X, Tang Y, Liu M, Lian Y, Liu P, Li R, Lu S, Tang F*, Qiao J*, and Xie X. S*. Live births after simultaneous avoidance of monogenic diseases and chromosome abnormality by next generation sequencing with linkage analyses. PNAS (2015), 112: 15964-15969.
    93. Guo F, Yan L, Guo H, Li L, Hu B, Zhao Y, Yong J, Hu Y, Wang X, Wei Y, Wang W, Li R, Yan J, Zhi X, Zhang Y, Jin H, Zhang W, Hou Y, Zhu P, Li J, Zhang L, Liu S, Ren Y, Zhu X, Wen L, Gao Y, Tang F *, Qiao J *. The transcriptome and DNA methylome landscapes of human primordial germ cells. Cell (2015), 161(6):1437-52. Highlighted by Ferdinand von Meyenn & Professor Wolf Reik, Cell (2015).
    94. Zhang Y, Chen Q, Zhang H, Wang Q, Li R, Jin Y, Wang H, Ma T*, Qiao J*, Duan E*. Aquaporin-dependent excessive intrauterine fluid accumulation is a major contributor in hyper-estrogen induced aberrant embryo implantation. Cell Res (2015), 25(1):139-142.
    95. Zhao Y, Zhang C, Huang Y, Yu Y, Li R, Li M, Liu N, Liu P, Qiao J*. Up-Regulated expression of WNT5a increases inflammation and oxidative stress via PI3K/AKT/NF-kappab signaling in the granulosa cells of PCOS patients. J Clin Endocrinol Metab (2015), 100(1):201-211.
    96. Zhao H, Zhao Y, Li T, Li M, Li J, Li R, Liu P, Yu Y, Qiao J*. Metabolism alteration in follicular niche: The nexus among intermediary metabolism, mitochondrial function, and classic polycystic ovary syndrome. Free Radic Biol Med (2015), 86: 295-307.
    97. Fan Y, Zhao HC, Liu JQ, Tan T, Ding T, Li R, Zhao Y, Yan J, Sun XF, Yu Y, Qiao J*. Aberrant expression of maternal Plk1 and Dctn3 results in the developmental failure of human in-vivo- and in-vitro-matured oocytes. Sci Rep (2015), 5: 8192
    98. Yu Y, Chang L, Zhao H, Li R, Fan Y, Qiao J*. Chromosome microduplication in somatic cells decreases the genetic stability of human reprogrammed somatic cells and results in pluripotent stem cells. Sci Rep (2015), 5:10114.
    99. Zhu J, Zhuang X, Chen L, Liu P*, Qiao J*. Effect of embryo culture media on percentage of males at birth. Hum Reprod (2015), 30(5):1039-1045.
    100. Lin S, Li R, Zheng X, Chi H, Ren X, Yang R, Liu P, Qiao J*. Influence of embryo culture medium on incidence of ectopic pregnancy in in vitro fertilization. Fertil Steril (2015), 104:1442-1445.
    101. Li M, Lin S, Chen Y, Zhu J, Liu P, Qiao J*. Value of transferring embryos that show no evidence of fertilization at the time of fertilization assessment. Fertil Steril (2015), 104:607-611.
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    105. Zhuang XJ, Tang WH, Liu CY, Zhu JL, Feng X, Yan J, Lian Y, Liu P, Qiao J*. Identification and Characterization of Xlr5c as a Novel Nuclear Localization Protein in Mouse Germ Cells. PloS One (2015), 10: e130087.
    106. Huang Y, Yu Y, Gao J, Li R, Zhang C, Zhao H, Zhao Y, Qiao J*. Impaired oocyte quality induced by dehydroepiandrosterone is partially rescued by metformin treatment. PloS One (2015), 10:e122370.
    107. Zhen X, Wu B, Wang J, Lu C, Gao H, Qiao J*. Increased incidence of mitochondrial Cytochrome c Oxidase 1 gene mutations in patients with primary ovarian insufficiency. PloS One (2015), 10:e132610.
    108. Lu CL, Yan J, Zhi X, Xia X, Wang TR, Yan LY, Yu Y, Ding T, Gao JM, Li R, Qiao J*. Basic fibroblast growth factor promotes macaque follicle development in vitro. Reproduction (2015), 149(5):425-433.
    109. Yu Y, Gao Q, Zhao HC, Li R, Gao JM, Ding T, Bao SY, Zhao Y, Sun XF, Fan Y, Qiao J*. Ascorbic acid improves pluripotency of human parthenogenetic embryonic stem cells through modifying imprinted gene expression in the Dlk1-Dio3 region. Stem Cell Res Ther (2015), 6(1):69.
    110. Xia X, Yin T, Yan J, Yan L, Jin C, Lu C, Wang T, Zhu X, Zhi X, Wang J, Tian L, Liu J, Li R, Qiao J*. Mesenchymal stem cells enhance angiogenesis and follicle survival in human cryopreserved ovarian cortex transplantation. Cell Transplant (2015), 24:1999-2010.
    111. Huang Y, Zhao Y, Yu Y, Li R, Lin S, Zhang C, Liu P, Qiao J*. Altered amphiregulin expression induced by diverse luteinizing hormone receptor reactivity in granulosa cells affects IVF outcomes. Reprod Biomed Online (2015), 30(6):593–601.
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    113. Guo YL, You K, Geng L, Qiao J*. Clinical Performance of APTIMA Human Papillomavirus (HPV) 16 18/45 mRNA Genotyping Testing for the Detection of Cervical Intraepithelial Neoplasia 3 (CIN3) or Cancer in a Select Group of Chinese Women. Pathol Oncol Res (2015), 2015:1-6.
    114. Xu H, Li R, Qiao J*. Homeodomain interacting protein kinase 2 is downregulated through the peroxisome proliferator-activated receptor gamma signaling pathway in an insulin-resistant population. J Diabetes Investig (2015), 6:594-596.
    115. Huang J, Zhao N, Wang X, Qiao J*, Liu P*. Chromosomal characteristics at cleavage and blastocyst stages from the same embryos. J Assist Reprod Genet (2015), 32:781-787.
    116. Cheng C, Zhang H, Zhao Y, Li R, Qiao J*. Paternal history of diabetes mellitus and hypertension affects the prevalence and phenotype of PCOS. J Assist Reprod Genet (2015), 32: 1731-1739.
    117. Li J, Li R, Yu H, Zhao S, Yu Y, Qiao J*. The relationship between serum anti-Mullerian hormone levels and the follicular arrest for women with polycystic ovary syndrome. Syst Biol Reprod Med (2015), 61:103-109.
    118. Liang C, Liang H, Yang Y, Ping L, Jie Q*. Mutation analysis of two families with inherited congenital cataracts. Mol Med Rep (2015), 12:3469-3475.
    119. Yang R, Yang S, Li R, Chen X, Wang H, Ma C, Liu P, Qiao J*. Biochemical pregnancy and spontaneous abortion in first IVF cycles are negative predictors for subsequent cycles: an over 10,000 cases cohort study. Arch Gynecol Obstet (2015), 292:453-458.
    120. Yang S, Pang T, Li R, Yang R, Zhen X, Chen X, Wang H, Ma C, Liu P, Qiao J*. The individualized choice of embryo transfer timing for patients with elevated serum progesterone level on the HCG day in IVF/ICSI cycles: a prospective randomized clinical study. Gynecol Endocrinol (2015), 31:355-358.
    121. Lin S, Li R, Zheng X, Wang L, Ren X, Chen L, Liu Q, Liu P, Qiao J*. Impact of hepatitis B virus carrier serostatus on neonatal outcomes after IVF-ET. Int J Clin Exp Med (2015), 8:6206-6211.
    122. Yang S, Li R, Chen XN, Fu Y, Yi M, Ma CH, Liu P, Qiao J*. Acute cerebral thrombosis following ovarian hyperstimulation syndrome: a case report. Chin Med J (Engl) (2015), 128:3383-3384.
    123. Yang R, Li HZ, Qiao J*. Clinical Features of an Unrecognized 21-hydroxylase deficiency woman during controlled ovarian hyperstimulation. Chin Med J (Engl) (2015), 128:2412-2413.
    124. Dang Y, Yan L, Hu B, Fan X, Ren Y, Li R, Lian Y, Yan J, Li Q, Zhang Y, Li M, Ren X, Huang J, Wu Y, Liu P, Wen L, Zhang C, Huang Y*, Tang F*, Qiao J*. Tracing the expression of circular RNAs in human pre-implantation embryos. Genome Biol (2016),17(1):130.
    125. Zhang L, Xue X, Yan J, Y YanL, Jin XH, Zhu XH, He ZZ, Liu J, Li R, Qiao J*. L-proline: a highly effective cryoprotectant for mouse oocyte vitrification. Sci Rep (2016), 6:26326.
    126. Yuan YF, Ren YX, Yuan P, Yan LY, Qiao J*. TRAIP is involved in chromosome alignment and SAC regulation in mouse oocyte meiosis. Sci Rep (2016), 6:29735.
    127. Huang S, Pang YL, Yan J, Lin S, Zhao Y, Lei L, Yan L, Li R, Ma C, Qiao J*. Fractalkine restores the decreased expression of StAR and progesterone in granulosa cells from patients with polycystic ovary syndrome. Sci Rep (2016), 6:26205.
    128. Wang H, Gao H, Chi H, Zeng L, Xiao W, Wang Y, Li R, Liu P, Wang C, Tian Q, Zhou Z, Yang J, Liu Y, Wei R, Mol BWJ, Hong T, Qiao J*. Effect of Levothyroxine on Miscarriage Among Women With Normal Thyroid Function and Thyroid Autoimmunity Undergoing In Vitro Fertilization and Embryo Transfer. JAMA (2017), 318(22):2190-2198
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    130. Li L, Dong J, Yan L, Yong J, Liu X, Hu Y, Fan X, Wu X, Guo H, Wang X, Zhu X, Li R, Yan J, Wei Y, Zhao Y, Wang W, Ren Y, Yuan P, Yan Z, Hu B, Guo F, Wen L, Tang F*, Qiao J*. Single-Cell RNA-Seq Analysis Maps Development of Human Germline Cells and Gonadal Niche Interactions. Cell Stem Cell (2017), 20(6):858-873.
    131. Gao S, Yan L, Wang R, Li J, Yong J, Zhou X, Wei Y, Wu X, Wang X, Fan X, Yan J, Zhi X, Gao Y, Guo H, Jin X, Wang W, Mao Y, Wang F, Wen L, Fu W, Ge H*, Qiao J*, Tang F*. Tracing the temporal-spatial transcriptome landscapes of the human fetal digestive tract using single-cell RNA-sequencing. Nat Cell Biol (2018), 20:721-734.
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      著作譯作
      一、主編
      1. 喬傑主編，《生殖醫學臨床診療常規》（中華醫學會繼續醫學教育教材），人民軍醫出版社，2013年6月，ISBN978-7-5091-6706-9
      2. 李蓉、喬傑主編。《生殖內分泌疾病診斷與治療》北京大學醫學部出版社。2013年3月，ISBN 978-7-565-90460-8
      3. 楊菁、張蔚、喬傑、孫瑩璞主編。《新編婦產科實習醫生手冊》人民衛生出版社。2012年7月，ISBN 978-7-117-15083-5
      4. 馬彩虹、喬傑主編。《生殖醫學微創手術學》北京大學醫學部出版社。2012年2月，ISBN 978-7-565-90335-9
      5. 李力、喬傑主編。《實用生殖醫學》人民衛生出版社。2012年3月，ISBN 978-7-117-14477-3
      6. 喬傑主編，多囊卵巢綜合徵，2010年1月第一版，ISBN978-7-81116-705-4，北京大學醫學出版社
      7. 喬傑主編，多囊卵巢綜合徵的診治進展，2010年4月第一版， ISBN978-7-89477-187-22，清華同方光碟電子出版社
      8. 喬傑主編，生殖醫學臨床新進展，2010年8月第一版，ISBN978-7-89477-227-53、清華同方光碟電子出版社
      9. 喬傑主編，蘇萍副主編。《生殖工程學》。人民衛生出版社。2007年7月，ISBN 978-7-117-08886-2/R.
      10. 喬傑主編。《婦產科教學案例選編》。北京大學醫學部出版社。2007年9月，ISBN 978-7-811-16182-3
      11. 喬傑主編。《不孕症與試管嬰兒》。北京大學醫學部出版社。2002年3月，ISBN 978-7-81071-284-2
      二、主譯
      1. 喬傑主譯。《不孕症》。人民衛生出版社。2006年7月第一版，ISBN 978-7-117-07738-7.
      2. 喬傑、楊孜主譯。《卵巢和子宮癌》。石油工業出版社。2001年1月第一版，ISBN978-7-502-13161-6.
      3. 喬傑主譯。《臨床生殖醫學與手術》。北京大學醫學部出版社。2010年1月第一版，ISBN 978-7-811-16494-7.
      4. 喬傑主譯。《奈特婦產科彩色圖譜》。人民衛生出版社。2007年7月第一版，ISBN 978-7-117-08444-4.
      三、副主編
      1. 曹澤毅主編, 喬傑副主編。《婦產科學》（衛生部十一五規劃教材）人民衛生出版社。2008年9月，ISBN 978-7-117-10271-1
      2. 董悅，魏立惠主編, 喬傑副主編。《婦產科學》（北京大學醫學部7年制教材）。北京大學醫學部出版社，2002年7月。ISBN 978-7-810-71368-9
      3. 李美芝主編，王藹明，喬傑，李英副主編。《婦科內分泌學》。人民軍醫出版社。2001年4月，ISBN 978-7-801-57163-01
      4. 魏麗惠主編,王建六，喬傑，陳倩副主編。《婦產科急症診斷與治療》。世界圖書出版公司，2003年7月。ISBN 978-7-506-25042-9
      四、參編
      1. 張麗珠主編, 喬傑，陳秉楓，顧方穎，李美芝，李曉紅，林其德，劉嘉茵參編。《臨床生殖內分泌與不育症》。科學出版社。2001年 3月第一版，2006年4月第二版，ISBN 978-7-030-16394-3
      2. 熊承良主編，喬傑參編. 臨床生殖醫學. 人民衛生出版社. 2007年7月，ISBN 978-7-117-08800-8.衛生部“十一五”規劃教材，全國高等醫藥教材建設研究會規劃教材
      3. 陳子江主編，喬傑參編，婦科內分泌診治新進展，2009年11月第一版，ISBN978-7-900220-24-0，中華醫學電子音像出版社
      4. 周應芳等主編，喬傑參編.婦產科熱點問題聚焦.北京大學醫學出版社.2006年1月第一版.ISBN 7-81071-760-X.
      5. 廖秦萍主編, 薛鳳霞、陳倩、喬傑參編。《婦產科學》（5年制衛生部推薦教材）。北京大學醫學部出版社， 2002年11月，ISBN 978-7-810-71345-0
      6. 楊冬梓，石一復主編，喬傑參編。《小兒和青春期婦科學》。人民衛生出版社。2003年11月第一版，ISBN 978-7-117-05791-2.
      7. 張麗珠主編，喬傑參編. 臨床生殖內分泌與不育症. 科學出版社. 2001年 3月第一版，2006年4月第二版，ISBN 7-03-016394-X
      8. 王世閬主編，喬傑參編.卵巢疾病.人民衛生出版社.2004年1月第一版.ISBN 7-117-05773-4/R.5774.
      9. 夏恩蘭主編, 喬傑參編. 婦科內鏡學. 人民衛生出版社.2001年4月.ISBN 7-117-04218-4.
      科普宣傳
      文章
      《生命時報》---老懷不上的三大原因
      《科技日報》---“全面二孩之後”，生還是不生？
      書籍
      喬傑，李蓉, 《如何保存生育力》, 北京大學醫學出版社, 2017年,ISBN 9787565917295
      喬傑著，編著還有：劉平、李蓉、李百花、姜輝、遲洪濱等，《備孕加油站》，人民衛生出版社，2016年3月，ISBN 9787555100539
      喬傑、賀宏瓊主編，《新家庭，新計畫——貴州省生育關懷指南》，上海科學技術出版社，2015年7月，ISBN 9787547826751R.928
      媒體
      好大夫網站：---PCOS患者如何懷孕
      央視新聞直播間---女性最佳生育年齡
      央視養生堂---祝你好孕
      報刊
      《醫學參考報》
      《生育力保存手冊》

      科研項目

      1. 科技部973計畫首席：雌性生育力維持調節機制研究及生殖資源庫建立。
      2. “十一五”國家科技支撐計畫：多囊卵巢綜合徵診斷及防治新技術新方法的研究。
      3. 國家傑出青年基金：套用代謝組學研究多囊卵巢綜合徵。
      4. 國家自然科學基金-創新研究群體科學基金：女性生殖細胞發育與生殖遺傳疾病。
      5. 國家自然科學基金重點項目：人卵泡體內及體外生長發育的基因表達譜及調控機制的研究。
      6. 國家自然科學基金：LHR和EGFR信號傳導通路在多囊卵巢綜合徵卵泡發育障礙中的研究。
      7. 國家自然科學基金課題：PCOS患者脂代謝異常的相關研究。
      8. 國家自然科學基金課題：PCOS患者發病的遺傳機制的DNA微陣列研究。
      9. 國家自然科學基金：多囊卵巢綜合徵的遺傳機制的探討。
      10. 國家自然科學基金課題：Leptin與PCOS發病相關關係的研究。
      11. 教育部創新團隊發展計畫：生殖內分泌與輔助生殖相關研究。
      12. 衛生部中國不孕不育流行病學調研項目。
      13. 衛生部公益項目：輔助生育技術診療常規和標準的制定與推廣套用。
      14. 首都醫學發展科研基金聯合攻關項目：北京市已婚育齡婦女生育力現狀調查及影響因素研究。
      15. 衛生部科教司項目：人類輔助生殖技術和精子庫相關技術規範修訂。
      16. 北京市管理專項基金：北京市輔助生育技術管理規範的制定。
      17. 北京市自然科學基金：CD36基因與多囊卵巢綜合徵的相關性研究。
      18. 教育部博士點基金：不同疾病狀態蛋白表達異常的相關研究。
      19. 教育部留學回國人員基金：多囊卵巢綜合徵發病機制的研究。
      20. 教育部高校博士點基金：PCOS不同疾病狀態表達異常的相關研究。
      21. 教育部青年教師獎基金：多囊卵巢綜合徵的基礎與臨床研究。
      22. 高等學校博士學科點專項科研基金醫學優先發展領域：利用小鼠模型及人卵母細胞體外成熟體系評價磷酸二酯酶（PDE）3抑制劑作為潛在避孕藥物的可行性與安全性。
      23. 教育部博士點基金：多囊卵巢綜合徵卵巢胰島素抵抗發病機制的研究。
      24. 台大醫學院合作建設項目：建立女性多囊卵巢綜合徵疾病多能型幹細胞系及雌性生殖細胞定向分化的研究。

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