唐惠儒，國家傑出青年科學基金獲得者、英國皇家化學會會士、復旦大學特聘教授。現承擔國家重點研發計畫、國家自然科學基金重大項目、國家創新群體、市級重大專項等課題。
基本介紹
- 中文名：唐惠儒
- 出生日期：1966年
- 職業：教師
- 主要成就：“新世紀百千萬人才工程”國家級人選稱號
研究方向,個人簡介,獲獎情況,主要論文,
研究方向
研究代謝物結構與功能30年，正發展高通量超靈敏代謝組學技術、代謝組與轉錄組/蛋白質組/微生物組等數據整合技術，研究肥胖等重大疾病發生髮展的代謝組基礎。曾主持完成國家傑出青年科學基金、肥胖等973項目課題多項。現承擔國家重點研發計畫、國家自然科學基金重大項目、國家創新群體、市級重大專項等課題。
個人簡介
1994年獲倫敦大學博士學位。
1992-2000年英國BBSRC食品研究所Research Scientist、Senior Scientist。
2001-2005年英國帝國理工學院生物醫學部Senior Scientist。
2005-2014年中科院武漢物數所研究員、博士生導師、研究部副主任、中科院生物磁共振分析重點實驗室主任。
2014年復旦大學生命科學學院。曾任英國NHS、科技部973及蛋白質重大計畫等評審專家、J Proteome Res編委。在Nature等上發表SCI論文180餘篇，被引7千餘次。獲批發明專利4項。部分工作被Science、Nature等作為“研究亮點”專文評述。現任中國生物物理學會理事、代謝組學分會會長、自由基生物學及醫學分會常務理事、生物磁共振專委會委員，中國抗癌協會腫瘤代謝專業委員會常務理事，中國營養學會基礎營養學分會理事，Metabolomics、Curr Metabolomics、Arch Pharm和《基礎醫學與臨床》等編委，Nutrition & Metabolism等副主編。
獲獎情況
（2005）英國皇家化學會會士。
（2008）國家傑出青年科學基金。
（2009）“新世紀百千萬人才工程”國家級人選稱號。
（2010）王天眷波譜學獎。
（2011）武漢市優秀科技工作者。
主要論文
1. J.H. Xue, et al, “A vitamin-C-derived DNA modification catalysed by an algal TET homologue”,Nature, 569:581–585, 2019.
2. C.X. Liu, et al, “Metabolic changes ofFusarium graminearuminduced by TPS gene deletion”.J Proteome Res,doi.org/10.1021/acs.jproteome.9b00259, 2019
3. H. Lin, et al, “Alterations of bile acids and gut microbiota in obesity induced by high fat diet in rat mode”,J Agric Food Chem, 67:3624-3632. 2019
4.L.M. Zhang, et al, “Metabolomics reveals that dietary ferulic acid and quercetin modulate metabolic homeostasis in rats”,J Agric Food Chem,66, 1723−1731, 2018
5. J.B. Gou, et al, “Discovery of a non-stereoselective cytochrome P450 catalyzing either 8α- or 8β- hydroxylation of germacrene A acid from the Chinese medicinal plant,Inula hupehensis”,Plant J, 93:92-106, 2018.
6. F.F. Chen, et al, “Combined metabonomic and quantitative RT-PCR analyses revealed metabolic reprogramming associated withFusarium graminearumresistance in transgenicArabidopsis thaliana”,Frontiers Plant Science, 8:2177, 2018.
7. X.C. He, et al “Influence of genotype and environment on volatile profile ofValerianae jatamansiRhizoma et Radix”,Front Plant Sci, 9:1003, 2018.
8. Q. Wang, et al, “Interspecies developmental differences in metabonomic phenotypes ofLycium ruthenicumandL. barbarumfruits”,J Proteome Res,17:3223-3236, 2018
9. Q.F. Wan, et al, "QuantitativeC traces of glucose fate in hepatitis B virus infected hepatocytes",Anal Chem, 89:3293–3299, 2017
10.J. Wang, et al, "Simultaneous quantification of amino metabolites in multiple metabolic pathways using ultra-high performance liquid chromatography with tandem-mass spectrometry",Sci Rep, 7:1435 2017.
11. Y.L. Hu, et al, “Biological effects of amphiphilic copolymer nanoparticle-encapsulated multi-target chemotherapeutic drugs on MCF-7 human breast cancer cells,Metabolomics, 13:49. 2017
12. C.X. Liu, et al, "Dynamic metabolic responses of brown planthoppers towards susceptible and resistant rice plants",Plant Biotechnol J, 15:1346–1357, 2017.
13. H.D. Li, et al, "Decreased glutathione biosynthesis contributes to EGFR T790M-driven erlotinib resistance in non-small cell lung cancer",Cell Discov, 2:16031, 2016.
14. S. Xu, et al, "Tumor growth affects the metabonomic phenotypes of multiple mouse non-involved organs in an A549 lung cancer xenograft model",Sci Rep, 6:28057, 2016.
15. Y. Tian, et al "Tissue metabonomic phenotyping for diagnosis and prognosis of human colorectal cancer",Sci Rep, 6:20790; doi: 10.1038/srep20790, 2016.
16. Z.G. Liu, et al, "Metabolic characteristics of 16HBE and A549 cells exposed to different surface modified gold nanorods",Adv Healthcare Mat, 5:2363–2375, 2016
17. H. Lin, et al, "Correlations of fecal metabonomic and microbiomic changes induced by high-fat diet in the pre-obesity state",Sci Rep, 6:21618, doi: 10.1038/srep21618, 2016.
18. J.F. Wu, et al, "Metabolomics insights into the modulatory effects of long-term low calorie intake in mice",J Proteome Res,15:2299–2308, 2016.
19. J.F. Wu, et al, "Gender differences of peripheral plasma and liver metabolic profiling in APP/PS1 transgenic AD mice",Neurosci, 332:160-169, 2016.
20. C.X. Liu, et al, "Reprogramming of seed metabolism facilitates pre-harvest sprouting resistance of wheat",Sci Rep, 6:20593; doi: 10.1038/srep20593, 2016.
21. Y. Kumar, et al, "Fusarium oxysporummediates systems metabolic reprogramming of chickpea roots as revealed by a combination of proteomics and metabolomics",Plant Biotechnol J, 14:1589-1603, 2016.
