南雨辰

南雨辰

南雨辰,男,1985年3月出生,甘肅天水人,美國馬里蘭大學分子病毒學博士學位,陝西省青年百人計畫入選者; 西北農林科技大學副教授博士生導師 。

基本介紹

  • 中文名:南雨辰
  • 出生地:甘肅天水
  • 出生日期:1985年3月
  • 畢業院校:美國馬里蘭大學
  • 學位/學歷:博士
  • 職業:教師
  • 專業方向:分子病毒學
人物經歷,研究方向,參講課程,科研項目,學術兼職,獲得專利,代表性論文,

人物經歷

2003年-2007年:西北農林科技大學動物醫學專業本科;
2007年-2009年:西北農林科技大學預防獸醫學碩士(出國直博未獲碩士學位);
2009年-2014年:美國馬里蘭大學分子病毒學,博士(Ph. D.);
2014年-2015年:美國馬里蘭大學,博士後;
2015年至今:西北農林科技大學,副教授,博士生導師;
2017年:入選陝西省委組織部第九批“青年百人計畫”;

研究方向

(1)戊型肝炎病毒(HEV)與宿主細胞相互作用機理;
(2)具備干擾素誘導表型及鑑別標記的豬繁殖與呼吸綜合徵病毒(PRRSV)新型疫苗開發
(3)抗PRRSV廣譜中和抗體中和PRRSV感染機制及識別抗原表位的鑑定
(4)豬重大疫病全宿主源基因工程抗體的研發

參講課程

《獸醫學專題》(博士生);《獸醫免疫學》(本科生、研究生);《免疫生物學》(本科生);《免疫與健康》(選修)

科研項目

2015年9月入職西北農林科技大學動物醫學院,目前從事家畜重大病毒性疫病致病機制研究,自入職以來主持國家自然科學基金面上項目(31672534),國家十三五重點研發計畫動物疫病生物防治性製劑研製與產業化專項課題(2017YFD0501004),中國科協青年人才托舉計畫,留學人員科技活動擇優資助項目及校級引進人才科研啟動經費多項。
(1)西北農林科技大學引進人才科研啟動經費(2015.9-2019.9):戊型肝炎致病機制;100萬;主持;
(2)科技部十三五國家重點研發計畫“動物疫病生物防治性製劑研製與產業化項目-課題4新型治療性動物基因工程抗體研製(課題編號:2017YFD0501004)”(2017.7-2020.12):320萬;主持;
(3)國家自然科學基金面上項目(2017.1-2020.12):豬戊型肝炎病毒抑制宿主幹擾素信號通路機制;61萬(批准號碼:31672534);主持;
(4)陝西省人才專項經費(2017.7-2020.12):20萬;主持;

學術兼職

(1)2012起:美國病毒學會(American Society of Virology)正式會員(非學生會員或聯合會員)
(2)2016年起;國家自然科學基金生命科學八處基金評議專家
(3)兼任下列雜誌特邀審稿人( Ad hoc Reviewer )
Virology, (病毒學;SCI影響因子3.35)
American Journal of Translation Research (美國轉化醫學雜誌;SCI影響因子3.146)
Beneficial Microbes (益生菌雜誌;SCI影響因子3.301)
International Journal of Molecular Medicine (國際分子醫學雜誌;SCI影響因子2.348)
Medical Science Monitor (醫學科學檢測;SCI影響因子1.45)
Evidence based Complementary and Alternative medicine(循證替代醫學雜誌;SCI影響因子1.931)
World Journal of Gastroenterology (世界消化醫學雜誌;SCI影響因子2.787)
Virus Research(病毒學研究;SCI影響因子2.87)
Virology Journal(病毒學雜誌;SCI影響因子2.09)
Veterinary Microbiology, (獸醫微生物學;SCI影響因子2.56)
PLoS One, (公共科學圖書館 綜合;SCI影響因子3.03)
Biomedical Research International, (國際生物醫學研究;SCI影響因子2.134)
Veterinary Immunology and Immunopathology, (動物免疫及免疫病理學,SCI影響因子1.9)

獲得專利

United States Patent Granted (美國國家專利局專利號碼:8906385B2): An Interferon-inducing Porcine Reproductive and Respiratory Syndrome Virus Isolate. Patent application granted. (申請日期 filed date: Dec 3, 2012, 批准日期granted date Oct 16, 2014專利生效日期Dec 9, 2014,專利保護期20年)

代表性論文

2017年
[1].Taofeng Du, Yuchen Nan, Shuqi Xiao, Qin Zhaoand En-Min Zhou; Antiviral Strategies against PRRSV Infection, Trends in Microbiology, 2017, (共同第一作者;影響因子:11.02)
[2].Yuchen NanChunyan Wu, GuoqianGu, Weirao Sun and En-Min Zhou; Improved Vaccine against PRRSV: Current progress and future perspective, Frontiers in Microbiology, 2016, (影響因子:4.02)
[3].Liping Yang, Rong Wang, Zexu Ma, Yueqiang Xiao, Yuchen Nan, Yu Wang, Shaoli Lin and Yan-Jin Zhang. Porcine Reproductive and Respiratory Syndrome Virus Antagonizes JAK/STAT3 Signaling via Nsp5 by Inducing STAT3 Degradation, Journal of Virology, 2017, 91, (影響因子:4.6)
[4].ShahidFaraz Syed, Yani Sun, TaofengDua, Yiyang Chen, Baoyuan Liu, XinjieWanga,Huixia Li, Yuchen Nan, En-Min Zhou and Qin Zhao. Evaluation of recombinant Chinese avian hepatitis E virus (CaHEV) ORF2and ORF3 proteins for protection of chickens against CaHEV infection, Vaccine, 2017,(35)3482–3489,(影響因子:3.235)
[5]. Zexu Ma, Ying Yu, Yueqiang, Xiao, TanjaOpriessnig, Rong Wang, Lipiong Yang, Yuchen Nan, Siba K Samal, Patrick G Halbur and Yan-Jin Zhang, The middle half genome of interferon-inducing porcine reproductive and respiratory syndrome virus strain A2MC2 is essential for interferon induction, Journal of General Virology, 2017,(影響因子:3.18)
2016年
[1]. Yuchen Nan and Yan-Jin Zhang; Molecular Biology and Infection of Hepatitis E Virus, Frontiers in Microbiology, 2016, (通訊作者;影響因子:4.12)
[2]. YonglinYang,Shaoli Lin,Yuchen Nan, Zexu Ma, Liping Yang, and Yan-Jin Zhang; A Linear Surface Epitope in a Proline-Rich Region of ORF3 Product of Genotype 1 Hepatitis E Virus. Viruses 8(8). 2016, doi: 10.3390/v8080227,(影響因子:3.042)
[3]. JimingGao, ShuqiXiao,Yihong Xiao, XinjieWang, Zhang C, Qin Zhao, Yuchen Nan , BaichengHuang , HongliangLiu, Liu N, Lv J, Du T, Sun Y, Mu Y, Wang G, Syed SF, Zhang G, Hiscox JA, Goodfellow I, Zhou EM. 2016. MYH9 is an Essential Factor for Porcine Reproductive and Respiratory Syndrome Virus Infection. Scientific Report 6:25120;(影響因子:5.228)
[4].YonglinYang, Yuchen Nan, Cai, Jie, Xu, Jiling, Zuhu Huang, XubingCai, The Thr to Met substitution of amino acid 118 in Hepatitis B virus surface Antigen escapes from immune assay based screening of blood Donors, Journal of General Virology; 2016;97:1210-1217;(影響因子:3.192)
[5]. Yueqiang Xiao, Zexu Ma , Rong Wang, Liping Yang, Yuchen Nan, Yan-Jin Zhang, Downregulation of protein kinase PKR activation by porcine reproductive and respiratory syndrome virus at its early stage Infection, Veterinary Microbiology, 2016, 187: 1-7;(影響因子:2.564)
[6]. Zexu Ma , Ying Yu, Yueqiang Xiao, TanjaOpriessnig, Rong Wang, Liping Yang, Yuchen Nan, Siba K. Samal, Patrick Gerard Halbur and Yan-Jin Zhang, Sustaining Interferon Induction by a High-Passage Atypical Porcine Reproductive and Respiratory Syndrome Virus Strain, Scientific Reports, 2016, 6:36312;(影響因子:5.228)
2015年
[1]. Yuchen Nan ,Ma, Zexu,Kannan, Harilakshmi,Stein, David A,Iversen,Patrick ,Meng, Xiang-Jin,Zhang, Yan-Jin, Inhibition of hepatitis E virusreplication by peptide-conjugated morpholino oligomers.,AntiviralResearch, 2015, 120: 134-139; (影響因子:4.909)
[2]. New insights into virus–cell interactions during HEV infection: The double roles of HEV in IFNs induction (邀稿文章). Chunyan Wu, Yuchen Nan and Yan-Jin Zhang;Future Virology; 2015;10(4): 439-448 (共同第一作者) (影響因子:1.0)
2014年
[1]. Yuchen Nan, Guoxin Nan and Yan-Jin Zhang: Interferon Induction and Antagonism by RNA Viral Pathogens. Viruses;2014, 6 (12), 4999-5027(影響因子:3.042)
[2]. Yuchen Nan, Ying Yu, Zexu Ma, Sunil Khattar, Brenda Fredericksen, andYan-Jin Zhang: Hepatitis E Virus Inhibits Type I Interferon Induction by ORF1 Product.Journal of Virology;2014; 88(15): 01935-14;(影響因子:4.606)
[3]. Yuchen Nan, Zexu Ma, Rong Wang, Ying Yu, andYan-Jin Zhang: Enhancement of interferon induction by ORF3 product of hepatitis E virus. Journal of Virology; 2014; 88(15):8696-705;(影響因子:4.606)
2013年
[1]. Rong Wang, Yueqiang Xiao, TanjaOpriessnig, Yi Ding, Ying Yu, Yuchen Nan, Zexu Ma, Patrick G Halbur, Yan-Jin Zhang: Enhancing neutralizing antibody production by an interferon-inducing porcine reproductive and respiratory syndrome virus strain.Vaccine; 2013; 31(47):5534-43. ;(影響因子:3.413)
[2]. Rong Wang, Yuchen Nan, Ying Yu, Zengqi Yang, andYan-Jin Zhang: Variable interference with interferon signal transduction by different strains of porcine reproductive and respiratory syndrome virus.Veterinary Microbiology; 2013; 166(3-4):493-503.;(影響因子:2.564)
[3]. Ying Yu, Rong Wang, Yuchen Nan, andYan-Jin Zhang: Induction of STAT1 Phosphorylation at Serine 727 correlates with elevation of inflammatory gene expression by PRRSV.PLoS One 2013; 8(4):e61967. doi: 10.1371/journal.pone.0061967;(影響因子:3.057)
[4].Rong Wang, Yuchen Nan, Ying Yu, and Yan-Jin Zhang:Porcine Reproductive and Respiratory Syndrome Virus Nsp1β Inhibits Interferon-Activated JAK/STAT Signal Transduction by Inducing Karyopherin-α1 Degradation, Journal of Virology 2013; 87(9):5219-28.;(影響因子:4.606)
2012年
[1].Yuchen Nan, Rong Wang, Meiyan Shen, Kay S. Faaberg, Siba K. Samal, and Yan-Jin Zhang: Induction of Type I Interferons by a Novel Porcine Reproductive and Respiratory Syndrome Virus Isolate. Virology 2012; 432:261-270;(影響因子:3.200)
[2]. Yanjin Zhang, Deendayal Patel, Yuchen Nan andSumin Fan: Inhibition of Kaposi's sarcoma-associated herpesvirus by morpholino oligomers. International Journal of Molecular Medicine, 2012,30:S33-S33; (影響因子:2.348)
[3].KritRitthipichai, Yuchen Nan, IoannisBossis, Yan-Jin Zhang: Viral FLICE Inhibitory Protein of Rhesus Monkey Rhadinovirus Inhibits Apoptosis by Enhancing Autophagosome Formation. PLoS ONE 2012; 7(6): e39438. doi:10.1371/journal.pone.0039438;(影響因子:3.057)
2011年
[1].Yan-Jin Zhang, Deendayal Patel, Yuchen Nan, and Sumin Fan: Inhibition of Early Lytic Genes of Kaposi’s Sarcoma-Associated Herpesvirus by Antiviral Morpholino Oligomers Leads to Engraftment Suppression of Primary Effusion Lymphoma in SCID Mice. Antiviral Therapy 2011; 16:657-66;(影響因子:3.774)
2010年
[1].Deendayal Patel,Yuchen Nan,Meiyan Shen,KritRitthipichai,Xiaoping Zhu,andYan-Jin Zhang: Porcine Reproductive and Respiratory Syndrome Virus Inhibits Type I IFN Signaling by Blocking STAT1/STAT2 Nuclear Translocation,Journal of Virology,2010. 84(21):11045-11055;(共同第一作者) (影響因子:5.06)
[2].Yuchen Nan,Deendayal Patel andYan-Jin Zhang: Inhibition of KSHV-associated lymphoma engraftment in SCID mouse by morpholino oligomers,Infectious Agents and Cancer,2010. 5(Suppl 1);(影響因子:1.718)

相關詞條

熱門詞條

聯絡我們