何心偉

何心偉，博士，安徽師範大學化學與材料科學學院碩士生導師。

基本介紹

• 中文名：何心偉
• 畢業院校：安徽師範大學
• 學位/學歷：博士
• 職業：教師
• 任職院校：安徽師範大學化學與材料科學學院

教育經歷

博士(安徽師範大學，2015年)

碩士(安徽師範大學，2009年)

學殼射士(安徽師範大學，2003年)

工作經歷

2015年12月—至今，安徽師範大學碩士生導師道辣拳

2003年07月—至今，安徽奔局詢懂師範大學助教，講師碑希疊，副教授(2015年)

主講課程

1.專業課：化工基礎/材料工程基礎/化工安全技術

2.實驗課：基礎化學實驗/綜合化學實驗/化工迎尋體雅專業實驗達煉狼/化工專淚晚只業實訓

3.選修課：諾貝爾獎與科學精神

學術成果

發表論文

46.Xinwei He, Pui Ying Choy, Man Pan Leung, On Ying Yuen, Tianyi Liu, Yongjia Shang, Fuk Yee Kwong.* A ZnI₂-Catalyzed Regioselective Cascade 1,4-Conjugate Addition/5-exo-digAnnulation Pathway for One-Pot Access to Heterobiaryl Frameworks.Chem. Commun.,2019,55, 15069-15072.

45.Xinwei He,* Mengqing Xie, Qiang Tang, Youpeng Zuo, Ruxue Li, and Yongjia Shang.* Catalyst-Free Synthesis of 2,3-Dihydrobenzofuransviaa Formal [4+1] Annulation of Propargylamines with Sulfur Ylides.J. Org. Chem.,2019,84, 11623−11638.

44. Youpeng Zuo,Xinwei He, * Yi Ning, Qiang Tang, Mengqing Xie, Wangcheng Hu and Yongjia Shang.* Substituent-Oriented C–N Bond FormationviaN–H Insertion or Wolff Rearrangement of 5-Aryl-1H-pyrazoles and Diazo Compounds.Org. Biomol. Chem.,2019,17, 9766–0771.

43. Qianqian Li,Xinwei He,* Jiajia Tao, Mengqing Xie, Hui Wang, Ruxue Li, and Yongjia Shang.* Base-mediated 1,4-Conjugate Addition/Intramolecular 5-exo-dig Annulation of Propargylamines with Benzoylacetonitriles and β-Keto Esters for Polysubstituted Furans and Furo[3,4-c]coumarins Formation.Adv. Synth. Catal.,2019,361, 1874-1886.

42. Yi Ning,Xinwei He, Youpeng Zuo, Panyuan Cai, Mengqing Xie, Jian Wang,* and Yongjia Shang.* Rhodium(II) Acetate-Catalysed Cyclization of Pyrazol-5-amine and 1,3-Diketone-2-diazo Compounds UsingN,N-Dimethylformamide as a Carbon-Hydrogen Source: Access to Pyrazolo[3,4-b]pyridines.Adv. Synth. Catal.,2019,361, 3518-3524.

41. Li-Qin Yan, Xiaoting Cai,Xinwei He, * Hui Wang, Mengqing Xie, Youpeng Zuo, Yongjia Shang. * Synthesis of 4-StyrylcoumarinsviaFeCl₃-Promoted Cascade Reactions of Propargylamines with β-Keto Esters.Org. Biomol. Chem.,2019,17, 4005–4013.

40.Xinwei He,* Yuhao Wu, Youpeng Zuo, Mengqing Xie, Ruxue Li and Yongjia Shang.* Transition Metal- and Oxidant-Free Sulfonylation of 1-Sulfonyl-1H-1,2,3-triazoles to Enols for the Synthesis of Sulfonate Derivatives.Synth. Commun.,2019,49, 959-972.

39.Xinwei He,* Guang Han, Youpeng Zuo, Yongjia Shang.* Rh(III)-catalyzed C-H Activation of Primary Benzamides and Tandem Cyclization with Cyclic 2-Diazo-1,3-diketones for the Synthesis of Isocoumarins.Tetrahedron,2018,74, 7082-7088.

38. Youpeng Zuo,Xinwei He, Yi Ning, Yuhao Wu,Yongjia Shang.* Selective Synthesis of AminoisoquinolinesviaRh(III)-catalyzed C-H/N-H Bond Functionalization ofN-Aryl Amidines with Cyclic 2-Diazo-1,3-diketones.J. Org. Chem.,2018,83, 13463-13472.

37.Xinwei He,* Hui Wang, Xiaoting Cai, Qianqian Li, Jiajia Tao, Yongjia Shang.* FeCl₃-promoted Tandem 1,4-Conjugate Addition/6-endo-digCyclyzation/Oxidation of Propargylamines and Benzoylacetonitriles/Malononitrile: Direct Access to Functionalized 2-Aryl-4H-chromenes.Org. Biomol. Chem.,2018,16, 7191-7202.

36. Chenli Fan,Xinwei He,* Yin Zuo, Yongjia Shang.* Synthesis of Oxazole and Furan DerivativesviaRh₂(OAc)₄-catalyzed C≡X Bond Insertion of Cyclic 2-Diazo-1,3-diketones with Nitriles and Arylacetylenes.Synth. Commun.,2018,48, 2782-2792.

35.XinweiHe,* Yuhao Wu, Wenjing Jin, Xiaoshun Wang, Cong Wu, Yongjia Shang.* Highly Efficient AgNO₃-catalyzed Approach to 2-(Benzo[d]azol-2-yl)phenols from Salicylaldehydes with 2-Aminothiophenol, 2-Aminophenol and Benzene-1,2-diamine.Appl. Orgnometal. Chem.,2018,32, e4284.

34.XinweiHe,* Yuhao Wu, Chenli Fan, Peng Lu, Youpeng Zuo, Yongjia Shang.* Oleylamine-catalyzed Tandem Knoevenagel/Michael Addition of 1,3-Cyclohexanediones with Aromatic Aldehydes.Chem. Res. Chin. Univ., 2018,34, 186-190.

33.Youpeng Zuo,Xinwei He, Yi Ning, Lanlan Zhang, Yuhao Wu, Yongjia Shang.* Divergent Synthesis of 3,4-Dihydrodibenzo[b,d]furan-1(2H)-ones and IsocoumarinsviaAdditive-controlled Chemoselective C-C or C-N Bond Cleavage.New J. Chem.,2018,42, 1673-1681.

32. Shuyan Yu,* Jingxin Wu,Xinwei He, Yongjia Shang.* Ferrocenyl Bisoxazoline as an Efficient Non-phosphorus Ligand for Palladium-catalyzed Copper-free Sonogashira Reaction in Aqueous Solution.Appl. Orgnometal. Chem.,2018,32, e4156.

31. Cuie Wang,* Ning Wang, Xinhua Liu, Peng Wan,Xinwei He, Yongjia Shang.* Expanding Application of Immobilized Candida Antarctica Lipase B: A Green Enzyme Catalyst for Knoevenagel Condensation Reaction.Fibers and Polymers,2018,19, 1611-1617.

30.Youpeng Zuo,Xinwei He, Yi Ning, Yuhao Wu, Yongjia Shang.* Rh(III)-Catalyzed C-H Activation/Intramolecular Cyclization: Access toN-Acyl-2,3-dihydro-1H-carbazol-4(9H)-ones from Cyclic 2-Diazo-1,3-diketones andN-Arylamides.ACS Omega,2017,2, 8507-8516.

29.Xinwei He,* Jiajia Tao, Hui Wang, Xiaoting Cai, Qianqian Li, Yongjia Shang.* Synthesis of polysubstituted phenyl acetatesviaFeCl₃-mediated domino reaction of 2-(aryl(piperidin-1-yl)methyl)phenols and 1,3-diketones.Tetrahedron,2017,73, 7017-7023.

28.Xinwei He,* Zhiyu Yu, Youpeng Zuo, Cheng Yang,Yongjia Shang.*Direct Carboxamidation of Cyclic 2-Diazo-1,3-diketones by Rh₂(OAc)₄-catalyzed Isocyanide Insertion-Hydrolysis.Org.& Biomol.Chem.,2017,15, 7127-7130.

27.Cheng Yang,Xinwei He(co-first author), Lanlan Zhang, Guang Han, Youpeng Zuo, Yongjia Shang.* Synthesis of Isocoumarins from Cyclic 2-Diazo-1,3-diketones and Benzoic AcidsviaRh(III)-catalyzed C-H Activation and Esterification.J. Org. Chem.,2017,82, 2081-2088.

26.Guanghao Shi,Xinwei He,Yongjia Shang,* Cheng Yang, Liwei Xiang. Oxidative Rearrangement of Isatins with Arylamines Using H₂O₂as Oxidant: A Facile Synthesis of Quinazoline-2,4-diones and Evaluation of Their Antibacterial Activity.Chin. J. Chem.,2017,35, 1835-1843.

25. Cuie Wang,Xinwei He, Xinhua Liu, Yongjia Shang.* DMAP-catalyzed cyclization of Schiff bases withalpha-halo ketones: Synthesis of 1,4-benzoxazines.Synth. Commun.,2017,47, 878-885.

24. Zhiqin Zhang,Xinwei He,Yongjia Shang,*Zhiyu Yu, Sufan Wang, Fuli Wu. Ferrocenyl-isoxazole Derivative: A NovelElectrochemical, Colorimetric, and Fluorescent Multiple Signal Probe for Highly Selective Recognition ofCuIons.Chem. Res.Chin. Univ.,2017,33, 31-35.

23.Xinwei He, Yao Zhou, Yongjia Shang,* Cheng Yang, Youpeng Zuo. Synthesis of 2-Arylimino-6,7-dihydrobenzo[d][1,3]oxathiol-4(5H)-onesviaRh₂(OAc)₄-catalyzed Reactions of Cyclic 2-Diazo-1,3-diketones with Aryl Isothiocyanates.ACS Omega,2016,1, 1277-1283.

22.Xinwei He, Jiajia Tao(co-first author), Xiaoqian Hu, Hui Wang, Yongjia Shang.* FeCl₃-mediated One-pot Domino Reactions for the Synthesis of 9-Aryl/9-Arylethynyl-2,3,4,9-tetrahydro-1H-xanthen-1-ones from Propargylic amines/Diaryl Amines and1,3-Cyclohexanediones.J. Org. Chem.,2016,81, 2062-2069.

21.何心偉,*胡小倩,陶佳佳,韓光,商永嘉.*鐵配合物催化的有機反應研究進展.有機化學,2016,36, 1465-1483.

20. Guanghao Shi,Xinwei He, Yongjia Shang,*Meihua Xie.* Combinatorial Synthesis of Spiro[indoline-3,2'-pyrrole] Derivativesviaa Three-component Reaction under Catalyst-free Conditions.RSC Adv.,2016,6, 10412-10418.

19. Guanghao Shi,Xinwei He, Yongjia Shang,* Liwei Xiang, Cheng Yang, Guang Han, Bing Du.* Synthesisof 3',4'-Diaryl-4'H-spiro[indoline-3,5'-[1',2',4']oxadiazol]-2-onesviaDMAP-catalyzed Domino Reactions and Their Antibacterial Activity.Chin. J. Chem.,2016,34, 901-909.

18. Chenli Fan,Xinwei He, Kaisheng Liao, Cuie Wang, Yongjia Shang.* DMAP-catalyzed Cascade Reaction for Efficient Synthesis of Naphthofurans.Chem. Res. Chin. Univ.,2016,32, 62-67.

17.何心偉,*陸鵬,謝慧敏,查陶春,商永嘉.無催化劑下2-氨基-3-氰基-5-氧代-5,6,7,8-四氫色烯衍生物的三組分合成.信陽師範學院學報(自然科學版),2016,29, 233-236.

16.Xinwei He, Yongjia Shang,* Yao Zhou, Zhiyu Yu, Guang Han, Wenjing Jin, Jiaojiao Chen. Synthesis of Coumarin-3-carboxylic EstersviaFeCl₃-Catalyzed Multicomponent Reaction of Salicylaldehydes, Meldrum’s Acid and Alcohols.Tetrahedron,2015,71, 863-868.

15. Yongjia Shang,* Xiaoqian Hu,Xinwei He,Jiajia Tao, Guang Han, Fuli Wu, Jie Wang. FeCl₃-Mediated Synthesis ofβ-Alkynyl KetonesviaDomino Nucleophilic-Substitution/Intramolecular-Cyclization/Reverse Claisen Condensation ofN-Cyclohexyl Propargylamines and 1,3-Diketones.J. Org. Chem.,2015,80, 4760-4765.

14.Xinwei He, Yongjia Shang,* Zhiyu Yu, Mei Fang,YaoZhou, Guang Han, Fuli Wu. FeCl₃-Catalyzed Four-component Nucleophilic Addition/Intermolecular Cyclization Yielding Polysubstituted Pyridine Derivatives.J. Org. Chem.,2014,79, 8882-8888.

13.Xinwei He, Zhenglei Yan, Xiaoqian Hu, Yin Zuo, Chang Jiang, Lei Jin, Yongjia Shang.* FeCl₃-Catalyzed Cascade Reaction: An Efficient Approach to Functionalized Coumarin Derivatives.Synth. Commun.,2014,44,1507-1514.

12. Manman Hu,Xinwei He, Zhiqiang Niu, Zhenglei Yan, Fuyin Zhou, Yongjia Shang.*Synthesis of 3,4,5-Trisubstituted Isoxazoles by 1,3-Dipolar Cycloaddition Reaction from α-Azidoacrylates and Aromatic Oxime.Synthesis,2014,46, 510-514.

11. Zhiqiang Niu,Xinwei He, Yongjia Shang.* Efficient Enantioselective Synthesis of DihydropyransviaOrganocatalytic Michael Addition Reaction.Tetrahedron: Asymmetry,2014,25, 796-801.

10.何心偉,周堯,於智宇,方梅,商永嘉. 2,5-二吡啶基-1,3,4-噁二唑的合成.阜陽師範學院學報(自然科學版),2014,31,26-28.

9.靳文靜,韓光,何心偉,*胡凱,商永嘉.異腈參與的多組分反應新進展.合成化學研究,2014,2,11-22.

8. Yongjia Shang,* Kaisheng Liao,Xinwei He, Jinsong Hu. One-Pot Synthesis of Disulfide-linkedN-Sulfonylazetidin-2-iminesviaa Copper-catalyzed Multicomponent Cascade Reaction.Tetrahedron,2013,69, 10134-10138.

7. Jiaping Wu, Yongjia Shang,* Cuie Wang,Xinwei He, Zhenglei Yan, Manman Hu,Fuyin Zhou. Synthesis of 3,4-Dihydro-2H-1,4-Benzo[b]thiazine DerivativesviaDABCO-Catalyzed One-Pot Three-Component Condensation Reactions.RSC Adv.,2013,3, 4643-4651.

6.何心偉,朱東盛,蔣暢,商永嘉.*室溫無溶劑無催化劑下的Knoevenagel縮合反應研究.有機化學研究,2013,1, 9-12.

5.Xinwei He, Yongjia Shang,* Jinsong Hu, Kai Ju, Wei Jiang, Sufang Wang. Syntheses ofN-sulfonyl-N,N-disubstitutedAmidinesviaa Three-component Free-radical Coupling Reaction of Tertiary Amines and Arenesulfonyl Azides with Terminal Alkynes,Sci. China Chem.,2012,55,214-222.

4. Yongjia Shang,* Lifen Wang,Xinwei He, Min Zhang.Novel Syntheses of Pyrrolo[2,1-a]isoquinolinesvia1,3-Dipolar Cycloaddition betweenN-Ylides and Alkynes.RSC Adv.,2012,2, 7681-76881.

3. Yongjia Shang,* Kai Ju,Xinwei He, Jinsong Hu, ShuyanYu, Min Zhang, Kaisheng Liao, Lifen Wang, Ping Zhang. Copper-Catalyzed Multicomponent Reaction: Synthesis of 4-Arylsulfonylimino-4,5-dihydrofuran Derivatives.J. Org. Chem.,2010,75, 5743-5745.

2.何心偉,金傑,王翠娥,商永嘉.*聚乙二醇支持的2,5-二取代異噁唑啉衍生物的液相合成.有機化學,2009,29, 55-60.

1. Yongjia Shang,*Xinwei He, Jinsong Hu, Jianwei Wu, Min Zhang, Shuyan Yu, Qianqian Zhang. Copper-Catalyzed Efficient Multicomponent Reaction: Synthesis of Benzoxazoline-Amidine Derivatives.Adv. Synth. Catal.,2009,351, 2709-2713.

會議論文

9.Mengqing Xie, Ruxue Li, Qiang Tang,Xinwei He.*Catalyst-Free Synthesis of 2,3-Dihydrobenzofuransviaa Formal [4+1] Annulation of Propargylamines with Sulfur Ylides.第十一屆全國有機化學學術會議,中國,上海, 2019年8月31日-9月3日.

8.Xinwei He,* Jiajia Tao, Hui Wang, Yongjia Shang.*Synthesis of Polysubstituted Phenyl AcetatesviaFeCl₃-mediated Domino Reaction of 2-(Aryl(piperidin-1-yl)methyl)phenols and 1,3-Diketones.第十屆全國有機化學學術會議,中國,深圳, 2017年12月19-21日.

7. Youpeng Zuo,Xinwei He, Yongjia Shang.*Divergent Synthesis of 3,4-Dihydrodibenzo[b,d]furan-1(2H)-ones and IsocoumarinsviaAdditive-controlled Chemoselective C-C or C-NBond Cleavage.第十屆全國有機化學學術會議,中國,深圳, 2017年12月19-21日.

6.Xinwei He, Yao Zhou, Yongjia Shang.*Synthesis of 2-Iimino-[1,3]oxathiolesviaRh₂(OAc)₄-catalyzed [3+2] Cycloaddition Reactions of Cyclic 2-Diazo-1,3-diketones with Aryl Isothiocyanates.第十九屆全國金屬有機化學學術討論會,中國,杭州,2016年10月28-31日.

5.Xinwei He, Xiaoqian Hu, Jiajia Tao, Hui Wang, Xiaoting Cai, Yongjia Shang.*FeCl₃-catalyzed Domino Reactions of Propargylic Amines and Activated Methylene Compounds.第十三屆全國有機合成化學學術研討會, P29,中國,揚州,2016年10月13-16日. (口頭報告).

4.Xiaoqian Hu,Xinwei He, Jiajia Tao, Yongjia Shang.*FeCl₃-catalyzed One-pot Tandem Reactions ofN-cyclohexyl Propargylaminesand 1,3-Diketones.第九屆全國有機化學學術會議,P360,中國,長春,2015年7月28-31日.

3.何心偉,商永嘉.*FeCl₃催化的基於芳醛、活潑亞甲基化合物的“一鍋”串聯反應/多組分反應合成香豆素/吡啶衍生物的研究.第十二屆江淮有機化學論壇,中國,蕪湖,2014年10月31日-11月2日.

2.何心偉,朱東盛,蔣暢,商永嘉.*室溫無溶劑無催化劑下的Knoevenagel縮合反應研究.第八屆有機化學學術會議暨首屆重慶有機化學國際研討會, P794,中國,重慶, 2013年10月17-20日.

1.Xinwei He, Kaisheng Liao, Zhenglei Yan, Fuyin Zhou, Manman Hu, Yongjia Shang.* One-step Synthesis of PolysubstitutedN-Sulfonylazetidin-2-iminesviaCopper-catalyzed Sequential Multicomponent/S-S Coupling Reaction.第十七屆全國金屬有機化學學術討論會,P209,中國,北京, 2012年10月19-22日.

科研項目

7.基於苯丙炔胺類化合物的親核取代-分子內環化串聯反應研究.安徽省自然科學基金面上項目(1808085MB41). 12萬, 2018.7-2021.6.主持,在研.

6.基於疊氮化合物和炔烴的多組分反應研究.安徽省高等學校自然科學研究重點項目(KJ2016A267). 6萬, 2016.1-2017.12.主持,在研.

5. FeCl₃催化的串聯反應合成含氮雜環化合物的研究.安徽師範大學博士科研啟動基金項目(2016XJJ110). 4萬, 2016.1-2018.12.主持,在研.

4. FeCl₃催化的串聯反應合成香豆素類化合物的套用研究,安徽省自然科學基金青年基金項目(1308085QB39), 5萬, 2013.7-2015.5,主持.

3. 3,4,5-三取代-2-噁唑烷酮衍生物的合成研究,安徽師範大學創新基金項目(2014cxjj12), 1.2萬, 2014.7-2016.6,主持.

2.一種香豆素類化合物的綠色合成研究,安徽師範大學創新基金項目(2011cxjj12), 1.0萬, 2012.1-2012.12,主持.

1. CuI催化的磺醯基脒類化合物及噁唑酮類衍生物的合成研究,安徽師範大學人才培育基金項目(2010rcpy041), 0.3萬, 2011.1-2012.12,主持.

專利成果

7.葉青青,左有鵬,何心偉,商永嘉. 1,2,3-三取代中氮茚衍生物及其製備方法.中國發明專利,專利號: 201810293794.3,公開日: 2018.09.14.

6.李欠欠,何心偉,陶佳佳,商永嘉.多取代呋喃衍生物及其製備方法.中國發明專利,專利號: 201810227907.X,公開日: 2018.08.24.

5.武玉豪,何心偉,左有鵬,商永嘉.香豆素-4-磺酸酯衍生物及其製備方法.中國發明專利,專利號: 201810034868.1,公開日: 2018.07.20.

4.左有鵬,何心偉,商永嘉.異香豆素衍生物的製備方法.中國發明專利,專利號: 201710416486.0,公開日: 2017.09.01.

3.何心偉,靳文靜,陳嬌嬌,商永嘉.一種香豆素-3-羧酸酯衍生物的製備方法.中國發明專利,專利號: 201310642930.2,公開日: 2014.03.12.

2.何心偉,商永嘉,琚凱. 3,4,5-三取代噁唑烷酮類化合物及其製備方法.中國發明專利,專利號: 201410557565.X,公開日: 2015.02.04.

1.趙敏,商永嘉,何心偉,孫宇.絮凝劑組合物,中國發明專利,專利號: 201110222749.7,公開日: 2011. 12. 28.

出版著作

1. Pui Ying Choy,Xinwei He, Fuk Yee Kwong.* Chapter 2: Palladacycles as Precatalysts for Heck and Sonogashira Cross-Coupling Reactions.Palladacycles: Catalysis and Beyond, Burlington: Elsevier,2019. pp. 21-173.

榮譽獎項

2019年獲安徽省“教壇新秀”稱號

2019年獲安徽師範大學首屆“郭銳評、陳禮勤獎教金”突出貢獻獎

2019年獲安徽省第四屆普通高校青年教師教學競賽一等獎

2019年獲安徽師範大學第九屆青年教師教學基本功大賽三等獎

2019年獲安徽師範大學化學與材料科學學院第十一屆青年教師講課大賽一等獎

2018年獲安徽省科學技術獎三等獎(排名第三)

2017年獲安徽師範大學化學與材料科學學院第六屆“最受本科生喜歡的青年教師”稱號

2016年獲安徽師範大學化學與材料科學學院第五屆“最受本科生喜歡的青年教師”稱號

2015年獲安徽省第八屆自然科學優秀學術論文三等獎(排名第一)

2015年獲安徽師範大學“教壇新秀”稱號

2015年獲安徽師範大學化學與材料科學學院第四屆“最受本科生喜歡的青年教師”稱號

2014年獲安徽師範大學第四屆青年教師教學基本功大賽三等獎

2014年獲安徽師範大學化學與材料科學學院第六屆青年教師講課大賽一等獎

2012年獲安徽省第七屆自然科學優秀學術論文三等獎(排名第三)

42. Yi Ning,Xinwei He, Youpeng Zuo, Panyuan Cai, Mengqing Xie, Jian Wang,* and Yongjia Shang.* Rhodium(II) Acetate-Catalysed Cyclization of Pyrazol-5-amine and 1,3-Diketone-2-diazo Compounds UsingN,N-Dimethylformamide as a Carbon-Hydrogen Source: Access to Pyrazolo[3,4-b]pyridines.Adv. Synth. Catal.,2019,361, 3518-3524.

41. Li-Qin Yan, Xiaoting Cai,Xinwei He, * Hui Wang, Mengqing Xie, Youpeng Zuo, Yongjia Shang. * Synthesis of 4-StyrylcoumarinsviaFeCl₃-Promoted Cascade Reactions of Propargylamines with β-Keto Esters.Org. Biomol. Chem.,2019,17, 4005–4013.

40.Xinwei He,* Yuhao Wu, Youpeng Zuo, Mengqing Xie, Ruxue Li and Yongjia Shang.* Transition Metal- and Oxidant-Free Sulfonylation of 1-Sulfonyl-1H-1,2,3-triazoles to Enols for the Synthesis of Sulfonate Derivatives.Synth. Commun.,2019,49, 959-972.

39.Xinwei He,* Guang Han, Youpeng Zuo, Yongjia Shang.* Rh(III)-catalyzed C-H Activation of Primary Benzamides and Tandem Cyclization with Cyclic 2-Diazo-1,3-diketones for the Synthesis of Isocoumarins.Tetrahedron,2018,74, 7082-7088.

38. Youpeng Zuo,Xinwei He, Yi Ning, Yuhao Wu,Yongjia Shang.* Selective Synthesis of AminoisoquinolinesviaRh(III)-catalyzed C-H/N-H Bond Functionalization ofN-Aryl Amidines with Cyclic 2-Diazo-1,3-diketones.J. Org. Chem.,2018,83, 13463-13472.

37.Xinwei He,* Hui Wang, Xiaoting Cai, Qianqian Li, Jiajia Tao, Yongjia Shang.* FeCl₃-promoted Tandem 1,4-Conjugate Addition/6-endo-digCyclyzation/Oxidation of Propargylamines and Benzoylacetonitriles/Malononitrile: Direct Access to Functionalized 2-Aryl-4H-chromenes.Org. Biomol. Chem.,2018,16, 7191-7202.

36. Chenli Fan,Xinwei He,* Yin Zuo, Yongjia Shang.* Synthesis of Oxazole and Furan DerivativesviaRh₂(OAc)₄-catalyzed C≡X Bond Insertion of Cyclic 2-Diazo-1,3-diketones with Nitriles and Arylacetylenes.Synth. Commun.,2018,48, 2782-2792.

35.XinweiHe,* Yuhao Wu, Wenjing Jin, Xiaoshun Wang, Cong Wu, Yongjia Shang.* Highly Efficient AgNO₃-catalyzed Approach to 2-(Benzo[d]azol-2-yl)phenols from Salicylaldehydes with 2-Aminothiophenol, 2-Aminophenol and Benzene-1,2-diamine.Appl. Orgnometal. Chem.,2018,32, e4284.

34.XinweiHe,* Yuhao Wu, Chenli Fan, Peng Lu, Youpeng Zuo, Yongjia Shang.* Oleylamine-catalyzed Tandem Knoevenagel/Michael Addition of 1,3-Cyclohexanediones with Aromatic Aldehydes.Chem. Res. Chin. Univ., 2018,34, 186-190.

33.Youpeng Zuo,Xinwei He, Yi Ning, Lanlan Zhang, Yuhao Wu, Yongjia Shang.* Divergent Synthesis of 3,4-Dihydrodibenzo[b,d]furan-1(2H)-ones and IsocoumarinsviaAdditive-controlled Chemoselective C-C or C-N Bond Cleavage.New J. Chem.,2018,42, 1673-1681.

32. Shuyan Yu,* Jingxin Wu,Xinwei He, Yongjia Shang.* Ferrocenyl Bisoxazoline as an Efficient Non-phosphorus Ligand for Palladium-catalyzed Copper-free Sonogashira Reaction in Aqueous Solution.Appl. Orgnometal. Chem.,2018,32, e4156.

31. Cuie Wang,* Ning Wang, Xinhua Liu, Peng Wan,Xinwei He, Yongjia Shang.* Expanding Application of Immobilized Candida Antarctica Lipase B: A Green Enzyme Catalyst for Knoevenagel Condensation Reaction.Fibers and Polymers,2018,19, 1611-1617.

30.Youpeng Zuo,Xinwei He, Yi Ning, Yuhao Wu, Yongjia Shang.* Rh(III)-Catalyzed C-H Activation/Intramolecular Cyclization: Access toN-Acyl-2,3-dihydro-1H-carbazol-4(9H)-ones from Cyclic 2-Diazo-1,3-diketones andN-Arylamides.ACS Omega,2017,2, 8507-8516.

29.Xinwei He,* Jiajia Tao, Hui Wang, Xiaoting Cai, Qianqian Li, Yongjia Shang.* Synthesis of polysubstituted phenyl acetatesviaFeCl₃-mediated domino reaction of 2-(aryl(piperidin-1-yl)methyl)phenols and 1,3-diketones.Tetrahedron,2017,73, 7017-7023.

28.Xinwei He,* Zhiyu Yu, Youpeng Zuo, Cheng Yang,Yongjia Shang.*Direct Carboxamidation of Cyclic 2-Diazo-1,3-diketones by Rh₂(OAc)₄-catalyzed Isocyanide Insertion-Hydrolysis.Org.& Biomol.Chem.,2017,15, 7127-7130.

27.Cheng Yang,Xinwei He(co-first author), Lanlan Zhang, Guang Han, Youpeng Zuo, Yongjia Shang.* Synthesis of Isocoumarins from Cyclic 2-Diazo-1,3-diketones and Benzoic AcidsviaRh(III)-catalyzed C-H Activation and Esterification.J. Org. Chem.,2017,82, 2081-2088.

26.Guanghao Shi,Xinwei He,Yongjia Shang,* Cheng Yang, Liwei Xiang. Oxidative Rearrangement of Isatins with Arylamines Using H₂O₂as Oxidant: A Facile Synthesis of Quinazoline-2,4-diones and Evaluation of Their Antibacterial Activity.Chin. J. Chem.,2017,35, 1835-1843.

25. Cuie Wang,Xinwei He, Xinhua Liu, Yongjia Shang.* DMAP-catalyzed cyclization of Schiff bases withalpha-halo ketones: Synthesis of 1,4-benzoxazines.Synth. Commun.,2017,47, 878-885.

24. Zhiqin Zhang,Xinwei He,Yongjia Shang,*Zhiyu Yu, Sufan Wang, Fuli Wu. Ferrocenyl-isoxazole Derivative: A NovelElectrochemical, Colorimetric, and Fluorescent Multiple Signal Probe for Highly Selective Recognition ofCuIons.Chem. Res.Chin. Univ.,2017,33, 31-35.

23.Xinwei He, Yao Zhou, Yongjia Shang,* Cheng Yang, Youpeng Zuo. Synthesis of 2-Arylimino-6,7-dihydrobenzo[d][1,3]oxathiol-4(5H)-onesviaRh₂(OAc)₄-catalyzed Reactions of Cyclic 2-Diazo-1,3-diketones with Aryl Isothiocyanates.ACS Omega,2016,1, 1277-1283.

22.Xinwei He, Jiajia Tao(co-first author), Xiaoqian Hu, Hui Wang, Yongjia Shang.* FeCl₃-mediated One-pot Domino Reactions for the Synthesis of 9-Aryl/9-Arylethynyl-2,3,4,9-tetrahydro-1H-xanthen-1-ones from Propargylic amines/Diaryl Amines and1,3-Cyclohexanediones.J. Org. Chem.,2016,81, 2062-2069.

21.何心偉,*胡小倩,陶佳佳,韓光,商永嘉.*鐵配合物催化的有機反應研究進展.有機化學,2016,36, 1465-1483.

20. Guanghao Shi,Xinwei He, Yongjia Shang,*Meihua Xie.* Combinatorial Synthesis of Spiro[indoline-3,2'-pyrrole] Derivativesviaa Three-component Reaction under Catalyst-free Conditions.RSC Adv.,2016,6, 10412-10418.

19. Guanghao Shi,Xinwei He, Yongjia Shang,* Liwei Xiang, Cheng Yang, Guang Han, Bing Du.* Synthesisof 3',4'-Diaryl-4'H-spiro[indoline-3,5'-[1',2',4']oxadiazol]-2-onesviaDMAP-catalyzed Domino Reactions and Their Antibacterial Activity.Chin. J. Chem.,2016,34, 901-909.

18. Chenli Fan,Xinwei He, Kaisheng Liao, Cuie Wang, Yongjia Shang.* DMAP-catalyzed Cascade Reaction for Efficient Synthesis of Naphthofurans.Chem. Res. Chin. Univ.,2016,32, 62-67.

17.何心偉,*陸鵬,謝慧敏,查陶春,商永嘉.無催化劑下2-氨基-3-氰基-5-氧代-5,6,7,8-四氫色烯衍生物的三組分合成.信陽師範學院學報(自然科學版),2016,29, 233-236.

16.Xinwei He, Yongjia Shang,* Yao Zhou, Zhiyu Yu, Guang Han, Wenjing Jin, Jiaojiao Chen. Synthesis of Coumarin-3-carboxylic EstersviaFeCl₃-Catalyzed Multicomponent Reaction of Salicylaldehydes, Meldrum’s Acid and Alcohols.Tetrahedron,2015,71, 863-868.

15. Yongjia Shang,* Xiaoqian Hu,Xinwei He,Jiajia Tao, Guang Han, Fuli Wu, Jie Wang. FeCl₃-Mediated Synthesis ofβ-Alkynyl KetonesviaDomino Nucleophilic-Substitution/Intramolecular-Cyclization/Reverse Claisen Condensation ofN-Cyclohexyl Propargylamines and 1,3-Diketones.J. Org. Chem.,2015,80, 4760-4765.

14.Xinwei He, Yongjia Shang,* Zhiyu Yu, Mei Fang,YaoZhou, Guang Han, Fuli Wu. FeCl₃-Catalyzed Four-component Nucleophilic Addition/Intermolecular Cyclization Yielding Polysubstituted Pyridine Derivatives.J. Org. Chem.,2014,79, 8882-8888.

13.Xinwei He, Zhenglei Yan, Xiaoqian Hu, Yin Zuo, Chang Jiang, Lei Jin, Yongjia Shang.* FeCl₃-Catalyzed Cascade Reaction: An Efficient Approach to Functionalized Coumarin Derivatives.Synth. Commun.,2014,44,1507-1514.

12. Manman Hu,Xinwei He, Zhiqiang Niu, Zhenglei Yan, Fuyin Zhou, Yongjia Shang.*Synthesis of 3,4,5-Trisubstituted Isoxazoles by 1,3-Dipolar Cycloaddition Reaction from α-Azidoacrylates and Aromatic Oxime.Synthesis,2014,46, 510-514.

11. Zhiqiang Niu,Xinwei He, Yongjia Shang.* Efficient Enantioselective Synthesis of DihydropyransviaOrganocatalytic Michael Addition Reaction.Tetrahedron: Asymmetry,2014,25, 796-801.

10.何心偉,周堯,於智宇,方梅,商永嘉. 2,5-二吡啶基-1,3,4-噁二唑的合成.阜陽師範學院學報(自然科學版),2014,31,26-28.

9.靳文靜,韓光,何心偉,*胡凱,商永嘉.異腈參與的多組分反應新進展.合成化學研究,2014,2,11-22.

8. Yongjia Shang,* Kaisheng Liao,Xinwei He, Jinsong Hu. One-Pot Synthesis of Disulfide-linkedN-Sulfonylazetidin-2-iminesviaa Copper-catalyzed Multicomponent Cascade Reaction.Tetrahedron,2013,69, 10134-10138.

7. Jiaping Wu, Yongjia Shang,* Cuie Wang,Xinwei He, Zhenglei Yan, Manman Hu,Fuyin Zhou. Synthesis of 3,4-Dihydro-2H-1,4-Benzo[b]thiazine DerivativesviaDABCO-Catalyzed One-Pot Three-Component Condensation Reactions.RSC Adv.,2013,3, 4643-4651.

6.何心偉,朱東盛,蔣暢,商永嘉.*室溫無溶劑無催化劑下的Knoevenagel縮合反應研究.有機化學研究,2013,1, 9-12.

5.Xinwei He, Yongjia Shang,* Jinsong Hu, Kai Ju, Wei Jiang, Sufang Wang. Syntheses ofN-sulfonyl-N,N-disubstitutedAmidinesviaa Three-component Free-radical Coupling Reaction of Tertiary Amines and Arenesulfonyl Azides with Terminal Alkynes,Sci. China Chem.,2012,55,214-222.

4. Yongjia Shang,* Lifen Wang,Xinwei He, Min Zhang.Novel Syntheses of Pyrrolo[2,1-a]isoquinolinesvia1,3-Dipolar Cycloaddition betweenN-Ylides and Alkynes.RSC Adv.,2012,2, 7681-76881.

3. Yongjia Shang,* Kai Ju,Xinwei He, Jinsong Hu, ShuyanYu, Min Zhang, Kaisheng Liao, Lifen Wang, Ping Zhang. Copper-Catalyzed Multicomponent Reaction: Synthesis of 4-Arylsulfonylimino-4,5-dihydrofuran Derivatives.J. Org. Chem.,2010,75, 5743-5745.

2.何心偉,金傑,王翠娥,商永嘉.*聚乙二醇支持的2,5-二取代異噁唑啉衍生物的液相合成.有機化學,2009,29, 55-60.

1. Yongjia Shang,*Xinwei He, Jinsong Hu, Jianwei Wu, Min Zhang, Shuyan Yu, Qianqian Zhang. Copper-Catalyzed Efficient Multicomponent Reaction: Synthesis of Benzoxazoline-Amidine Derivatives.Adv. Synth. Catal.,2009,351, 2709-2713.

會議論文

9.Mengqing Xie, Ruxue Li, Qiang Tang,Xinwei He.*Catalyst-Free Synthesis of 2,3-Dihydrobenzofuransviaa Formal [4+1] Annulation of Propargylamines with Sulfur Ylides.第十一屆全國有機化學學術會議,中國,上海, 2019年8月31日-9月3日.

8.Xinwei He,* Jiajia Tao, Hui Wang, Yongjia Shang.*Synthesis of Polysubstituted Phenyl AcetatesviaFeCl₃-mediated Domino Reaction of 2-(Aryl(piperidin-1-yl)methyl)phenols and 1,3-Diketones.第十屆全國有機化學學術會議,中國,深圳, 2017年12月19-21日.

7. Youpeng Zuo,Xinwei He, Yongjia Shang.*Divergent Synthesis of 3,4-Dihydrodibenzo[b,d]furan-1(2H)-ones and IsocoumarinsviaAdditive-controlled Chemoselective C-C or C-NBond Cleavage.第十屆全國有機化學學術會議,中國,深圳, 2017年12月19-21日.

6.Xinwei He, Yao Zhou, Yongjia Shang.*Synthesis of 2-Iimino-[1,3]oxathiolesviaRh₂(OAc)₄-catalyzed [3+2] Cycloaddition Reactions of Cyclic 2-Diazo-1,3-diketones with Aryl Isothiocyanates.第十九屆全國金屬有機化學學術討論會,中國,杭州,2016年10月28-31日.

5.Xinwei He, Xiaoqian Hu, Jiajia Tao, Hui Wang, Xiaoting Cai, Yongjia Shang.*FeCl₃-catalyzed Domino Reactions of Propargylic Amines and Activated Methylene Compounds.第十三屆全國有機合成化學學術研討會, P29,中國,揚州,2016年10月13-16日. (口頭報告).

4.Xiaoqian Hu,Xinwei He, Jiajia Tao, Yongjia Shang.*FeCl₃-catalyzed One-pot Tandem Reactions ofN-cyclohexyl Propargylaminesand 1,3-Diketones.第九屆全國有機化學學術會議,P360,中國,長春,2015年7月28-31日.

3.何心偉,商永嘉.*FeCl₃催化的基於芳醛、活潑亞甲基化合物的“一鍋”串聯反應/多組分反應合成香豆素/吡啶衍生物的研究.第十二屆江淮有機化學論壇,中國,蕪湖,2014年10月31日-11月2日.

2.何心偉,朱東盛,蔣暢,商永嘉.*室溫無溶劑無催化劑下的Knoevenagel縮合反應研究.第八屆有機化學學術會議暨首屆重慶有機化學國際研討會, P794,中國,重慶, 2013年10月17-20日.

1.Xinwei He, Kaisheng Liao, Zhenglei Yan, Fuyin Zhou, Manman Hu, Yongjia Shang.* One-step Synthesis of PolysubstitutedN-Sulfonylazetidin-2-iminesviaCopper-catalyzed Sequential Multicomponent/S-S Coupling Reaction.第十七屆全國金屬有機化學學術討論會,P209,中國,北京, 2012年10月19-22日.

科研項目

7.基於苯丙炔胺類化合物的親核取代-分子內環化串聯反應研究.安徽省自然科學基金面上項目(1808085MB41). 12萬, 2018.7-2021.6.主持,在研.

6.基於疊氮化合物和炔烴的多組分反應研究.安徽省高等學校自然科學研究重點項目(KJ2016A267). 6萬, 2016.1-2017.12.主持,在研.

5. FeCl₃催化的串聯反應合成含氮雜環化合物的研究.安徽師範大學博士科研啟動基金項目(2016XJJ110). 4萬, 2016.1-2018.12.主持,在研.

4. FeCl₃催化的串聯反應合成香豆素類化合物的套用研究,安徽省自然科學基金青年基金項目(1308085QB39), 5萬, 2013.7-2015.5,主持.

3. 3,4,5-三取代-2-噁唑烷酮衍生物的合成研究,安徽師範大學創新基金項目(2014cxjj12), 1.2萬, 2014.7-2016.6,主持.

2.一種香豆素類化合物的綠色合成研究,安徽師範大學創新基金項目(2011cxjj12), 1.0萬, 2012.1-2012.12,主持.

1. CuI催化的磺醯基脒類化合物及噁唑酮類衍生物的合成研究,安徽師範大學人才培育基金項目(2010rcpy041), 0.3萬, 2011.1-2012.12,主持.

專利成果

7.葉青青,左有鵬,何心偉,商永嘉. 1,2,3-三取代中氮茚衍生物及其製備方法.中國發明專利,專利號: 201810293794.3,公開日: 2018.09.14.

6.李欠欠,何心偉,陶佳佳,商永嘉.多取代呋喃衍生物及其製備方法.中國發明專利,專利號: 201810227907.X,公開日: 2018.08.24.

5.武玉豪,何心偉,左有鵬,商永嘉.香豆素-4-磺酸酯衍生物及其製備方法.中國發明專利,專利號: 201810034868.1,公開日: 2018.07.20.

4.左有鵬,何心偉,商永嘉.異香豆素衍生物的製備方法.中國發明專利,專利號: 201710416486.0,公開日: 2017.09.01.

3.何心偉,靳文靜,陳嬌嬌,商永嘉.一種香豆素-3-羧酸酯衍生物的製備方法.中國發明專利,專利號: 201310642930.2,公開日: 2014.03.12.

2.何心偉,商永嘉,琚凱. 3,4,5-三取代噁唑烷酮類化合物及其製備方法.中國發明專利,專利號: 201410557565.X,公開日: 2015.02.04.

1.趙敏,商永嘉,何心偉,孫宇.絮凝劑組合物,中國發明專利,專利號: 201110222749.7,公開日: 2011. 12. 28.

出版著作

1. Pui Ying Choy,Xinwei He, Fuk Yee Kwong.* Chapter 2: Palladacycles as Precatalysts for Heck and Sonogashira Cross-Coupling Reactions.Palladacycles: Catalysis and Beyond, Burlington: Elsevier,2019. pp. 21-173.

榮譽獎項

2019年獲安徽省“教壇新秀”稱號

2019年獲安徽師範大學首屆“郭銳評、陳禮勤獎教金”突出貢獻獎

2019年獲安徽省第四屆普通高校青年教師教學競賽一等獎

2019年獲安徽師範大學第九屆青年教師教學基本功大賽三等獎

2019年獲安徽師範大學化學與材料科學學院第十一屆青年教師講課大賽一等獎

2018年獲安徽省科學技術獎三等獎(排名第三)

2017年獲安徽師範大學化學與材料科學學院第六屆“最受本科生喜歡的青年教師”稱號

2016年獲安徽師範大學化學與材料科學學院第五屆“最受本科生喜歡的青年教師”稱號

2015年獲安徽省第八屆自然科學優秀學術論文三等獎(排名第一)

2015年獲安徽師範大學“教壇新秀”稱號

2015年獲安徽師範大學化學與材料科學學院第四屆“最受本科生喜歡的青年教師”稱號

2014年獲安徽師範大學第四屆青年教師教學基本功大賽三等獎

2014年獲安徽師範大學化學與材料科學學院第六屆青年教師講課大賽一等獎

2012年獲安徽省第七屆自然科學優秀學術論文三等獎(排名第三)